You are here

Drug Discovery

Impact

NEWS: 
In the Media
Media Outlet: 
Annals of Neurology
The Board of Trustees, Faculty and Staff of the Burke Medical Research Institute, an affiliate of Weill Cornell Medicine mourn the loss of our founder, friend and colleague.
Fletcher McDowell, M.D., Founder of Burke Medical Research Institute
EVENT: 
Weekly Seminar
Tuesday, May 2, 2017 - 12:30pm
Billings Building – Rosedale
EVENT: 
Weekly Seminar
Tuesday, March 21, 2017 - 12:30pm
Billings Building – Rosedale
EVENT: 
Weekly Seminar
Tuesday, May 9, 2017 - 12:30pm
Billings Building – Rosedale
RESEARCH PROJECT: 
In Progress
Thiamine (vitamin B1) deficiency (TD) produces a mild, chronic impairment of oxidative metabolism that models the diminished metabolism and reduced activities of the thiamine-dependent mitochondrial enzymes that occur in brain in several common age-related neurodegenerative disorders.
NEWS: 
Article

On March 2nd, a manuscript from the Burke Medical Research Institute describing a novel drug for improving outcomes following brain hemorrhage was published in Science’s sister journal, Science Translational Medicine.

BMRI Researchers Discover a Novel Drug to Prevent Brain Bleeding
PUBLICATION: 
Journal Article
Gibson GE, Hirsch JA, Fonzetti P, Jordan BD, Cirio RT, Elder J.
Ann N Y Acad Sci. 2016 Mar;1367(1):21-30. doi: 10.1111/nyas.13031. Epub 2016 Mar 11.
Abstract on PubMed
NEWS: 
In the Media
Media Outlet: 
Chemical & Engineering News
NEWS: 
In the Media
Media Outlet: 
ScienceDaily
PUBLICATION: 
Journal Article
Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR
Sci Transl Med. 2016 Mar 2;8(328):328ra29. doi: 10.1126/scitranslmed.aac6008.
Abstract on PubMed