Ratan Lab
Research Projects

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Research Projects

RESEARCH PROJECT: 
In Progress
Researchers have developed an in vitromodel to mimic hemorrhagic stroke using hemin, which induces cell death in various neuronal cell types that is rescued by PHD inhibitors.
RESEARCH PROJECT: 
In Progress
Intracerebral hemorrhage (ICH) accounts for about 15% of all strokes and has the highest mortality rates among strokes with up to 50% within 30 days after the insult. It is known to increase intracranial pressure and is associated with excitotoxicity, oxidative stress, and inflammation.
RESEARCH PROJECT: 
In Progress
Oxidative stress is an event associated with a variety of neurological disorders, including stroke. It occurs when neurons are unable to maintain reactive oxygen species (ROS) homeostasis.
RESEARCH PROJECT: 
In Progress
The human brain represents only 2% of the body weight but it utilizes around 20% of total body glucose. This shows how crucial glucose metabolism is for the proper functioning of neurons and other cell types in the brain.
RESEARCH PROJECT: 
In Progress
Histone deaceytlase (HDAC) inhibitors are a promising therapeutic of neurological diseases.

Associated

Conditions & Recovery

Stroke icon
Every 40 seconds someone has a stroke.
Neurodegenerative Diseases icon
Worldwide, 50 million people are living with Alzheimer's and other dementias.
Traumatic Brain Injury icon
In the U.S., over 5.3 million adults and children live with TBI.
Spinal Cord Injury icon
Around the world, between 300,000 and 500,000 people are living with a SCI.
Cerebral Palsy icon
Worldwide, over 18 million children and adults are living with CP.
Retinal Degenerative Diseases icon
Will double by 2050.
Motor Recovery Icon
Write and walk again.
Cognitive Recovery icon
Remember and talk clearly.