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Metabolism

Impact

NEWS: 
Article
The research team examined how myeloid cells can also facilitate repair by clearing debris and promoting tissue remodeling during the early stages of repair. The study showed that a transcription factor, hypoxia-inducible factor, which the Ratan lab has been studying for years, marks myeloid cells that are associated with good long term recovery.
Photo of Raj, Saravanan, Amit, and Yingxin
PUBLICATION: 
Case Report
Michael H. Askenase, Brittany A. Goods, Hannah E. Beatty, Arthur F. Steinschneider, Sofia E. Velazquez, Artem Osherov, Margaret J. Landreneau, Shaina L. Carroll, Tho B. Tran, Victor S. Avram, Riley S. Drake, G. James Gatter, Jordan A. Massey, Saravanan S. Karuppagounder, Rajiv R. Ratan, Charles C. Matouk, Kevin N. Sheth, Wendy C. Ziai, Adrian R. Parry-Jones, Issam A. Awad, Mario Zuccarello, Richard E. Thompson, Jesse Dawson, Daniel F. Hanley, J. Christopher Love, Alex K. Shalek, Lauren H. Sansing, MISTIE III Consortium, ICHseq investigators
Science Immunology 2021 Feb 19;6(56):eabd6279. doi: 10.1126/sciimmunol.abd6279. Epub 2021 Feb 19.
Full-Text on Pubmed Science Immunology
NEWS: 
In the Media
Media Outlet: 
CNN Health
Benfotiamine and Cognitive Decline in Alzheimer's Disease, a small exploratory clinical trial, conducted by Dr. Gary E. Gibson’s laboratory at the Burke Neurological Institute is listed in CNN Health’s article on ”Top 2020 health stories you may have missed because of Covid-19” under Advances in Alzheimer’s.
Gibson Team in the Lab
NEWS: 
Article
A small exploratory clinical trial conducted by Dr. Gary E. Gibson’s laboratory at the Burke Neurological Institute in collaboration with physicians at the Burke Rehabilitation Hospital, suggests that Benfotiamine is safe and potentially efficacious in improving cognitive outcomes among people living with Mild Cognitive Impairment and mild Alzheimer’s disease (AD).
Photo of Gibson Lab
PUBLICATION: 
Manuscript
Gary E Gibson, José A Luchsinger, Rosanna Cirio, Huanlian Chen, Jessica Franchino-Elder, Joseph A Hirsch, Lucien Bettendorff, Zhengming Chen, Sarah Flowers, Linda Gerber, Thomas Grandville, Nicole Schupf, Hui Xu, Yaakov Stern, Christian Habeck, Barry Jordan, Pasquale Fonzetti
J Alzheimers Dis . 2020 Oct 16. doi: 10.3233/JAD-200896. Online ahead of print.
Abstract on PubMed
EVENT: 
Weekly Seminar | Not Open to the Public
Tuesday, November 19, 2019 - 12:30pm
Billings Building – Rosedale
PUBLICATION: 
Opinion Article
Kumar A. Edited by Rajiv R. Ratan and Yutaka Yoshida
Curr Opin Neurol . 2019 Dec;32(6):815-821. doi: 10.1097/WCO.0000000000000752.
Abstract on PubMed
PUBLICATION: 
Opinion Article
Yoshida Y, Ratan RR.
Curr Opin Neurol. 2019 Oct 10. doi: 10.1097/WCO.0000000000000757. [Epub ahead of print]
Full-Text on Wolters Kluwer
EVENT: 
Weekly Seminar | Not Open to the Public
Tuesday, July 2, 2019 - 12:30pm
Billings Building – Rosedale
Dr. Field's Photo
PUBLICATION: 
Review
Yang Y, Gibson GE.
Neurochem Res. 2019 Oct;44(10):2346-2359. doi: 10.1007/s11064-019-02780-x. Epub 2019 Mar 22.
Abstract on PubMed