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Metabolism

Impact

Gibson Lab
PUBLICATION: 
Review
Gibson GE, Zhang H.
Interactions of oxidative stress with thiamine homeostasis promote neurodegeneration.
Neurochem Int. 2002 May;40(6):493-504. Review.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Book Chapter
Gibson GE, Zhang H.
Advances in Ginkgo Biloba Extract Research: Effects of Ginkgo biloba (EGb761) on metabolism of reactive oxygen species in fibroblasts from Alzheimer’s Disease patients and controls
Christen Y, Editeur S, editors. Marseille: Ipsen Foundation; 2001. Effects of Ginkgo biloba (EGb761) on metabolism of reactive oxygen species in fibroblasts from Alzheimer’s Disease patients and controls ; p.108-121.
Gibson Lab
PUBLICATION: 
Journal Article
Calingasan NY, Gibson GE.
Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism.
Brain Res. 2000 Dec 1;885(1):62-9.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Murphy EJ, Zhang H, Sorbi S, Rapoport SI, Gibson GE.
Phospholipid composition and levels are not altered in fibroblasts bearing presenilin-1 mutations.
Brain Res Bull. 2000 Jun;52(3):207-12.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Review
Blass JP, Sheu RK, Gibson GE.
Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise.
Ann N Y Acad Sci. 2000 Apr;903:204-21. Review.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Review
Calingasan NY, Gibson GE.
Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain.
Ann N Y Acad Sci. 2000 Apr;903:353-6. Review.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Calingasan NY, Huang PL, Chun HS, Fabian A, Gibson GE.
Vascular factors are critical in selective neuronal loss in an animal model of impaired oxidative metabolism.
J Neuropathol Exp Neurol. 2000 Mar;59(3):207-17.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Review
Gibson GE, Park LC, Sheu KF, Blass JP, Calingasan NY.
The alpha-ketoglutarate dehydrogenase complex in neurodegeneration.
Neurochem Int. 2000 Feb;36(2):97-112. Review.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Review
Gibson GE, Park LC, Zhang H, Sorbi S, Calingasan NY.
Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits.
Ann N Y Acad Sci. 1999;893:79-94. Review.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Park LC, Calingasan NY, Uchida K, Zhang H, Gibson GE.
Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture.
J Neurochem. 2000 Jan;74(1):114-24.
Abstract on PubMed

Causes

Stroke, Cognitive Recovery, Neurodegenerative Diseases