Cortico-motor assembloids: a human 3D multi-cellular platform to study spinal cord development and disease

EVENT:

Weekly Seminar | Not Open to the Public

Host:

Vibhu Sahni, Ph.D., Katherina Rees

Who Should Attend:

Researchers

Event Flyer:

andersen_11-11-25.pdf

Speakers

Jimena Andersen, Ph.D.

Assistant Professor

Department of Human Genetics

Emory University School of Medicine

Abstract

Research in the Andersen lab leverages the use of region-specific organoids and assembloids as windows into unique aspects of human biology.

Specifically, we are interested in understanding cell-cell interactions underlying the development and degeneration of motor neurons in the spinal cord.

Publications

Lisa Mapelli, Danila Di Domenico, Giacomo Sciacca, Francesco Mainardi, Alessandra Ottaviani, Anita Monteverdi, Mariateresa Tedesco, Chiara Rosa Battaglia, Simona Tritto, Mauro Gandolfo, Kilian Imfeld, Stefanie Kiderlen, Lukas Krainer, Chiara Cervetto, Manuela Marcoli, Anson Sing, Jimena Andersen, Fikri Birey, Steven A. Sloan, Alessandro Maccione, Egidio D'Angelo

Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays

PLOS ONE, 20(9):e0328903, 2025.

Ji-Il Kim, Yuki Miura, Min-Yin Li, Omer Revah, Sridhar Selvaraj, Fikri Birey, Xiangling Meng, Mayuri Vijay Thete, Sergey D. Pavlov, Jimena Andersen, Anca M. Pașca, Matthew H. Porteus, John R. Huguenard, Sergiu P. Pașca

Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway.

Neuron 112, 4048-4059, 2024

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Cortico-motor assembloids: a human 3D multi-cellular platform to study spinal cord development and disease

Speakers

Abstract

Publications

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