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Advancing Research In Rare Neurodegenerative Diseases: A Focus On Multiple System Atrophy
seminar-miriam-sklerov-011519.pdfSpeakers
Abstract:
Background and Purpose: Research in rare neurodegenerative diseases is often limited and difficult to undertake for many reasons. We will explore some of these challenges using multiple system atrophy as a model. Multiple system atrophy (MSA) is a devastating neurodegenerative condition that bears many similarities with Parkinson’s disease. Clinical trials in this disease have been historically limited despite the lack of effective available treatments.
Objectives:
- To provide an educational overview of multiple system atrophy (MSA)
- To discuss the importance of biomarkers in MSA research
- To explore the potential use of neuroimaging as a tool in MSA research
Methods: We will first learn about the pathophysiology and epidemiology of MSA to emphasize the importance of research in this disease. This will lead us to a discussion on the current obstacles we face in this area of research, as well as advances that may aid our endeavors.
Conclusions: Neuroimaging has provided a window into our knowledge of MSA and holds promise to become a useful marker of disease in this and other neurodegenerative conditions.
