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Alterations in Extracellular Vesicle Communication as a Cause of Neuromuscular Junction Dysfunction after Spinal Cord Injury

November 1, 2015 to October 31, 2017
Funding Status: 
Completed Project
Funding Agency: 
New York State Department of Health (NYSDOH)
Funding Institute: 
Spinal Cord Injury Research Board (SCIRB)
Grant Number: 
Contract Number: C30602-GG-3450000
Published Grant: 


The major goal of this project is to test the hypothesis that a specific signal, small, non-coding RNAs called microRNAs, are secreted from muscle cells to motor neurons and regulate the local events within neuronal axons. This signal is altered following SCI, resulting in changes to the appearance of and function of the NMJ. Dr. Hill's role is limited to generating SCI tissue.


Dianna's Photo
Associate Director
Lab Director
Laboratory for Axonal and RNA Biology
Assistant Professor
Principal Investigator


Conditions & Recovery

Spinal Cord Injury icon
Around the world, between 300,000 and 500,000 people are living with a SCI.
Pain and Sensory Recovery Icon
Pain free, touch and smell like before.