Our Research

The science behind hope

Hope demands brilliant science, and every day we translate groundbreaking research into promising neurological treatments. We put patients at the center of discovery by combining rigorous science and specialized clinics.

Research Labs

Laboratory for Neuronal Specification
Cave Lab studies mechanisms that regulate the proliferation and differentiation of adult neural stem cells to develop and treat of neurological disease or injury.
Preclinical Stroke Modeling Laboratory
Focused on preclinical stroke studies, Cho Lab closely examines stroke pathology to address the gap between preclinical and clinical settings for translational medicine.
Clinical Laboratory for Early Brain Injury Recovery
Friel Lab aims to improve hand function in children with cerebral palsy (CP). Our research focuses on the importance of motor activity in neurorehabilitation.
Laboratory for Mitochondrial Biology and Metabolic Dysfunction in Neurodegeneration
The goals of the Gibson Laboratory are to discover the underlying cause of age-related neurodegenerative diseases and to develop effective therapies.
Circuit Repair Laboratory
Hollis Lab studies the reorganization of neural circuits during learning and rehabilitation with a focus on the function of cortical motor networks after spinal cord injury.
Human Motor Recovery Laboratory

In the Human Motor Recovery Laboratory, we are studying the control of movements after neurological injury, particularly after stroke.

Laboratory for Visual Disease and Therapy
Prusky lab focuses on understanding the nature of adaptive change in the nervous system in animals to apply treatments of visual dysfunction in humans.
Laboratory for Redox Biology and Neural Protection and Repair
Ratan Lab's focus is to understand adaptive programs that facilitate the brain's ability to combat injury and to foster repair.
Visual Plasticity and Repair Laboratory
Sagdullaev Lab focuses on sensory signal processing, particularly on how fundamental yet simple synaptic mechanisms underlie our perception of the world around us.
Laboratory for Cell Fate Specification and Circuit Development
The research goal of Sahni Lab is to identify molecules that can be recruited to restore functions or to take on new functions.
Laboratory for Axonal and RNA Biology
Willis Lab focuses on sensory neuron axonal biology, particularly on how local events within the axon are important in driving normal and pathological behaviors. 
Neural Connectivity Development in Physiology and Disease Laboratory

The Yoshida Laboratory is interested in formation, function, and regeneration of motor circuits controlling locomotor and skilled movements.

Molecular Regeneration and Neuroimaging Laboratory
Zhong Lab focuses on elucidating the molecular mechanisms that drive and direct axon growth and regeneration during early development after injury or degenerative disease.

Research Centers & Clinical Research Programs

Burke-Blythedale Restorative Neurology Program
Improving neurorehabilitation treatments for children through advances in neuroscience.
Center Pain & Sensory Recovery
Pursuing new concepts to better understand how chronic pain establishes itself after trauma or disease, and to develop novel therapeutic approaches to improve the lives of pain patients.
Patient during TDCS Apraxia Study
Finding methods for the rehabilitation and recovery of speech and language disorders.
Patient using OptokineSys

The Burke Center for Vision Repair constitutes a collection of world-class vision research laboratories, a vision assessment core, a collaborative/contract research facility, a device development division, and a community outreach program.

Restorative Neurology Clinic
Offering breakthrough state-of-the-art robotic neurorehabilitation therapies to restore motor function for adults recovering from a neurological condition.