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Modulation of Cortical Networks, a New Approach to Spinal Cord Injury Rehabilitation

September 30, 2017 to June 30, 2022
Funding Status: 
Completed Project
Funding Agency: 
National Institutes of Health (NIH)
Funding Institute: 
National Institute of Neurological Disorders and Stroke (NINDS)
Grant Number: 
Published Grant: 


The proposed studies are innovative in that they shift the focus of spinal cord rehabilitation onto the circuit mechanisms of cortical network plasticity and will have far- reaching importance in translating treatments for both acute and chronic injuries to motor networks. The proposed studies are significant because they will elucidate the mechanisms by which circuit remodeling influences recovery, which will have far-reaching importance in translating treatments for both acute and chronic injuries to cortical motor networks. The expectation is that completion of the proposed research will generate new opportunities for pharmacological modulation and combinatorial treatments that enhance corticospinal axon regeneration while mediating cortical motor network reorganization.


Edmund's Photo
Lab Director
Circuit Repair Laboratory
Assistant Professor
Post-Doctoral Advancement Advisor
Principal Investigator


Conditions & Recovery

Motor Recovery Icon
Write and walk again.
Spinal Cord Injury icon
Around the world, between 300,000 and 500,000 people are living with a SCI.