Postdoctral fellows to study formation and regeneration of motor circuits at Burke / Weill Cornell White Plains, New York

The Neural Connectivity Development in Physiology and Disease Laboratory at the Burke Neurological Institute /Weill Cornell Medicine, led by Yutaka Yoshida, Ph.D., is currently seeking Postdoctoral Fellows with laboratory experience in neuroscience. We are interested in understanding neural circuits that control motor behaviors using a variety of techniques such as optogenetics, electrophysiology, Ca imaging, single cell RNA-seq, molecular biology, and mouse genetic. Any postdoctoral fellow with neuroscience experience is welcome to apply for this position to study motor circuits.

References)

1. Gu Z., Sarrad N., Ueno M., Liang M., Li J., Enquist L.W., Baccei M.R., Martin J.H., and Yoshida Y. (2017). Skilled movements require non-apoptotic Bax/Bak pathway-mediated corticospinal circuit reorganization. Neuron, 94, 626-641.

2. Gu Z., Kalamboglas J., Yoshioka S., Han W., Zhuo L., Imamura Kawasawa Y., Pochareddy S., LiZ., Liu F., Xu X., Wijeratne S., Ueno M., Blatz E., Salomone J., Kumanogoh A., Rasin M.R., Gebelein B., Weirauch M.T., Sestan N., Martin J.H., and Yoshida Y. (2017). Control of species-dependent cortico-motoneuronal connections underlying manual dexterity, Science, 357, 400-404.

3. Ueno M., Ueno-Nakamura, Y., Li J, Gu Z., Niehaus J., Maezawa M., Crone S.A., Goulding M., Baccei M.L., and Yoshida Y. (2018). Corticospinal circuits from the sensory and motor cortex differentially regulate skilled movements through distinct interneurons. Cell Reports, 23, 1286-1300.

4. Ueno M., Ueno-Nakamura Y., Niehaus J., Popovich P.G., and Yoshida Y. (2016). Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury. Nature Neuroscience, 19, 784-787

5. Imai F., Adam M., Potter S., and Yoshida Y. (2021). HoxD transcription factors define monosynaptic specificity sensory-motor connections in the developing spinal cord. Development, 148 (12): dev191122.

6. Nakamura Y., Ueno M., Niehaus J., Lang R., Zheng Y., and Yoshida Y. (2021). Modulation of both intrinsic and extrinsic factors synergistically promotes rewiring of corticospinal circuits after spinal cord injury. Journal of Neuroscience, 41 (50): 10247-10260.

7. Gu Z., Matsuura K., Letelier A, Basista M., Craig C., Imai F, and Yoshida Y. (2023). Axon fasciculation, mediated by transmembrane semaphorins, is critical for the establishment of segmental specificity of corticospinal circuits. Journal of Neuroscience, 43 (32): 5753-5768