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Neural Predictors of Hand Therapy Efficacy in Children with Cerebral Palsy

September 26, 2014 to June 30, 2019
Funding Status: 
Completed Project
Funding Agency: 
National Institutes of Health (NIH)
Funding Institute: 
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Grant Number: 
Published Grant: 


  1. How do motor circuits interact and change in response to intensive hand therapy?
  2. Does the efficacy of intensive hand therapy depend on laterality of the corticospinal tract that controls the affected hand?

The proposed experiments will answer these questions. Children are not little adults. Therapies for USCP must be built on a strong understanding of motor control in USCP. By identifying the neural circuit effects of CIMT vs. HABIT, we can tailor therapies to children most likely to benefit. This work will also provide a framework for developing new activity-based therapies for USCP.


Kathleen's Photo
Lab Director
Clinical Laboratory for Early Brain Injury Recovery
Associate Professor
Principal Investigator


Conditions & Recovery

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Write and walk again.
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Worldwide, over 24 million children and adults are living with CP.