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Principles and Applications of Closed-Loop Neural Interfaces

Speakers
Abstract
Recent years have seen substantial recent progress in technologies for monitoring and manipulating brain activity. Research in my lab focusses on neural interfaces that combine sensing and stimulation to allow continuous ‘closed-loop’ interactions with the nervous system. Such interfaces can act as neuroprosthetic devices to replace connections lost through injury, neurorehabilitation devices to drive plastic changes in brain circuits, and neuromodulation devices to regulate oscillatory dynamics. I will discuss example applications in the areas of spinal cord injury (Guiho et al. 2021), stroke (Hodkin et al. 2018) and epilepsy (Zaaimi et al. 2022), as well as describe recent efforts to develop a non-invasive closed-loop interface using music. Since many neurological conditions are increasingly seen as disorders of neural connectivity, plasticity and dynamics, closed-loop neural interfaces may in future have wide-ranging applications for repairing brain circuits, regulating brain activity and restoring brain function.