You are here

Motor Function and White Matter Outcomes Following an Intervention Targeting Skilled Lower Extremity Movement for Children with Bilateral CP

Weekly Seminar | Not Open to the Public
Who Should Attend: 


Eileen Fowler P.T., Ph.D.
Peter Shapiro Chair & Director of Research & Education
UCLA/OIC Center for Cerebral Palsy
Tarjan Center at UCLA


In spastic cerebral palsy, damage to descending corticospinal tracts of the immature brain results in reduced selective motor control. Selective motor control is the ability to produce isolated joint movement with the required speed, strength and reciprocity to perform a given task. When selective motor control is impaired, mass flexor and extensor patterns and undesired movements at non-agonist joints, including mirroring, often occur. In the lower extremities, selective motor control can be evaluated using clinical examination and biomechanical analyses. Abnormal coupled movement of the hip and knee during gait is a hallmark of poor selective motor control that can be studied using a dynamic systems approach. Obligatory mirroring further impairs functional performance and reduced motor output occurs when mirroring is inhibited. Preliminary results of a selective motor control intervention on motor performance and microstructure of brain white matter tracts will be presented.

Eileen Fowler P.T., Ph.D. Figure

Method to calculate relative phase angles between the hip and knee: A) time series kinematics, B) velocity-angle phase portraits, C) phase angles and D) relative phase angles. The minimum relative phase angle (MRP) indicates independence of the knee and hip joints during swing. Maximum independence = -180 degrees. Fowler EG and Goldberg EJ. Gait Posture 29:102-7, 2009


Fowler EG, Staudt LA, Greenberg MB.
Lower-extremity selective voluntary motor control in patients with spastic cerebral palsy: increased distal motor impairment.
Dev Med Child Neurol. 2010 Mar;52(3):264-9. doi: 10.1111/j.1469-8749.2009.03586.x.
Goldberg EJ, Requejo PS, Fowler EG.
Joint moment contributions to swing knee extension acceleration during gait in children with spastic hemiplegic cerebral palsy.
J Biomech. 2010 Mar 22;43(5):893-9. doi: 10.1016/j.jbiomech.2009.11.008. Epub 2009 Dec 16.
Goldberg EJ, Requejo PS, Fowler EG.
Joint moment contributions to swing knee extension acceleration during gait in individuals with spastic diplegic cerebral palsy.
Gait Posture. 2011 Jan;33(1):66-70. doi: 10.1016/j.gaitpost.2010.09.026. Epub 2010 Oct 29.


Tuesday, October 30, 2018 - 12:30pm


785 Mamaroneck Avenue
White Plains, NY 10605
United States
Conference Room: 
Alexander Building – Patient Dining Room

More Information

Conditions & Recovery

Cerebral Palsy icon
Worldwide, over 24 million children and adults are living with CP.
Motor Recovery Icon
Write and walk again.