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Motor Cortex and Spinal Cord Neuromodulation to Promote Motor Function After Injury

Weekly Seminar
Who Should Attend: 


Guest Speaker
Dr. John Martin's Photo
Professor, Molecular, Cellular and Biomedical Sciences


John (Jack) Martin is a Medical Professor at the City University of New York School of Medicine and the City College of New York’s Center for Discovery and Innovation. He received his Ph.D. in neurophysiology from Columbia University and received postdoctoral training at Rockefeller and Columbia Universities. Dr. Martin’s laboratory studies the neural circuits for movement from the dual perspectives of development and repair. His neural repair research leverages neuromodulatory strategies to promote durable plasticity to repair corticospinal system damage after injury and to restore movement control. His laboratory has discovered that CST neurons can be promoted to sprout axons and make functional connections after injury by increasing their activity, using electrical stimulation. This stimulation, in turn, promotes recovery of function after a brain or spinal cord injury.

Dr. John Martin's Figure


Jiang YQ, Sarkar A, Amer A, Martin JH.
Transneuronal Downregulation of the Premotor Cholinergic System After Corticospinal Tract Loss.
J Neurosci. 2018 Sep 26;38(39):8329-8344. doi: 10.1523/JNEUROSCI.3410-17.2018. Epub 2018 Jul 26.
Zareen N, Dodson S, Armada K, Awad R, Sultana N, Hara E, Alexander H, Martin JH.
Stimulation-dependent remodeling of the corticospinal tract requires reactivation of growth-promoting developmental signaling pathways.
Exp Neurol. 2018 Sep;307:133-144. doi: 10.1016/j.expneurol.2018.05.004. Epub 2018 May 2.
Jiang YQ, Zaaimi B, Martin JH.
Competition with Primary Sensory Afferents Drives Remodeling of Corticospinal Axons in Mature Spinal Motor Circuits.
J Neurosci. 2016 Jan 6;36(1):193-203. doi: 10.1523/JNEUROSCI.3441-15.2016.


Tuesday, December 17, 2019 - 12:30pm


785 Mamaroneck Avenue
White Plains, NY 10605
United States
Conference Room: 
Billings Building – Rosedale

More Information

Lindsey Echevarria