You are here

Independence of Neurons for Trophic Factors

Weekly Seminar | Not Open to the Public
Who Should Attend: 


Little is known about how neurons become independent of trophic support.  Answering this question will provide insight into how aging neurons avoid cell death and persist for a lifetime. An increased resistance to the loss of trophic factors represents a protective mechanism to prevent neurodegeneration.

Dr. Moses Chao's Figure


Abigail Mariga, Mariela Mitre, Moses V Chao
Consequences of brain-derived neurotrophic factor withdrawal in CNS neurons and implications in disease
Neurobiol Dis. 2017 Jan;97(Pt B):73-79. doi: 10.1016/j.nbd.2016.03.009. Epub 2016 Mar 22.
Abigail Mariga, Jiri Zavadil, Stephen D Ginsberg, Moses V Chao
Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function
Dev Neurobiol. 2015 Feb;75(2):173-92. doi: 10.1002/dneu.22216. Epub 2014 Aug 25.
Helen E Scharfman, Moses V Chao
The entorhinal cortex and neurotrophin signaling in Alzheimer's disease and other disorders
Cogn Neurosci. 2013;4(3-4):123-35. doi: 10.1080/17588928.2013.826184. Epub 2013 Aug 25.


Tuesday, February 22, 2022 - 12:30pm


Conference Room: 
Online Webinar

More Information

Darlene White

Conditions & Recovery

Neurodegenerative Diseases icon
Worldwide, 50 million people are living with Alzheimer's and other dementias.