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Effects of Bimanual Training

In-Progress / Currently Recruiting Participants

What Do We Do?

We are using targeted or untargeted transcranial direct current stimulation (tDCS) combined with hand-arm bimanual intensive therapy to observe the effects on upper extremity function and observe effects on corticospinal tract (CST) activity in children who have unilateral spastic cerebral palsy. In other words, we are observing whether these two therapies combined will improve connectivity between the brain and the affected limb. 

What should I expect at each visit?

In the pre- and post-training portions, children will be required to undergo various motor skill tests, a transcranial magnetic stimulation (TMS) session, and an MRI session. During the bimanual training, children will undergo a 20-minute tDCS session, during which they will begin their two hours of structured play and functional activities.


  • Pre-training assessments one week prior to bimanual training
  • Bimanual training 2 hours/day for 5 consecutive days (A total of 10 hours of training)
  • Post-training assessments immediately after bimanual training
  • A second round of post-training assessments six months after training

How Much Does It Cost?

  • Free of charge. Travel costs may be covered by the sponsor
  • Participants will receive renumeration for each TMS session


Age Range: 
6-18 Years Old
Both (Male and Female)
Inclusion Criteria: 

You may be eligible for this study if you meet the following requirements:

  • Have hemiplegic cerebral palsy
Trial Identifier: 
Cerebral Palsy

Study Locations

Burke Neurological Institute
785 Mamaroneck Avenue
White Plains, NY 10605
Teachers College, Columbia University
525 W. 120th Street Building 528, Room 1056C
New York, NY 10027