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Axonal Regeneration

Impact

Willis Lab
PUBLICATION: 
Journal Article
Wong VSC, Picci C, Swift M, Levinson M, Willis D, Langley B
Alpha-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin Associated Glycoprotein.
eNeuro. 2018 Feb 28;5(1). pii: ENEURO.0240-17.2018. doi: 10.1523/ENEURO.0240-17.2018. eCollection 2018 Jan-Feb.
Full-Text on Pubmed
EVENT: 
Weekly Seminar | Not Open to the Public
Biomechanical Forces Regulate Gene Transcription in Mammalian Neurons
Tuesday, February 6, 2018 - 12:30pm
Billings Building – Rosedale
Joseph R. Loverde, Ph.D.
Joseph R. Loverde, Ph.D.
EVENT: 
Weekly Seminar | Not Open to the Public
Influences of Neuronal Activity on Pain and Regeneration After Spinal Cord Injury
Tuesday, January 30, 2018 - 12:30pm
Billings Building – Rosedale
Armin Blesch, PhD
Armin Blesch, Ph.D.
Willis Lab
PUBLICATION: 
Review
Costa CJ, Willis DE.
To the End of the Line: Axonal mRNA transport and local translation in health and neurodegenerative disease.
Dev Neurobiol. 2018 Mar;78(3):209-220. doi: 10.1002/dneu.22555. Epub 2017 Nov 13.
Abstract on PubMed
GRANT: 
Federal
July 15, 2017 to June 30, 2022
Engaging Neuron-Intrinsic Signaling for Axon Growth After Spinal Cord Injury
Funding Status: 
Active Project
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Grant Number: 
R01 NS099568-01A1
Investigators: 
Jian Zhong, Ph.D.
Principal Investigator
Chris B. Schaffer, Ph.D.
Co-Investigator
David Putrino, Ph.D., P.T.
Co-Investigator
Dylan Edwards, Ph.D., P.T.
Consultant
Yoshida Lab
GRANT: 
Federal
April 1, 2017 to March 31, 2022
A Novel Combinatorial Approach to Restore Motor Function After Spinal Cord Injury
Funding Status: 
Active Project
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Grant Number: 
R01NS100772
Investigators: 
Yutaka Yoshida, Ph.D.
Principal Investigator
Willis Lab
PUBLICATION: 
Journal Article
Brochier C, Jones JI, Willis DE, Langley B.
Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration.
Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15220-5. doi: 10.1073/pnas.1509754112.
Full-Text on PubMed
Willis Lab
PUBLICATION: 
Review
Ma TC, Willis DE.
What makes a RAG regeneration associated?
Front Mol Neurosci. 2015 Aug 7;8:43. doi: 10.3389/fnmol.2015.00043. Review.
Abstract on PubMed
PUBLICATION: 
Journal Article
Carmel JB, Young W, Hart RP.
Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS.
Front Mol Neurosci. 2015 Jul 17;8:34. doi: 10.3389/fnmol.2015.00034.
Abstract on PubMed
PUBLICATION: 
Journal Article
Siddiq MM, Hannila SS, Carmel JB, Bryson JB, Hou J, Nikulina E, Willis MR, Mellado W, Richman EL, Hilaire M, Hart RP, Filbin MT.
Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System.
J Biol Chem. 2015 Jun 26;290(26):16343-56. doi: 10.1074/jbc.M114.630574.
Full-Text Article on PubMed

Causes

Motor Recovery, Pain & Sensory Recovery, Spinal Cord Injury