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Cell Death

Impact

Gibson Lab
PUBLICATION: 
Journal Article
Calingasan NY, Gibson GE.
Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism.
Brain Res. 2000 Dec 1;885(1):62-9.
Abstract on PubMed
Gibson Lab / Ratan Lab
GRANT: 
Federal
June 2, 1999 to April 30, 2015
Mitochondrial Dysfunction in Neurodegeneration of Aging
Funding Status: 
Completed Project
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Grant Number: 
P01AG014930
Investigators: 
Gary E. Gibson, Ph.D.
Principal Investigator
Rajiv R. Ratan, M.D., Ph.D.
Project Leader
Cho Lab
PUBLICATION: 
Journal Article
Son JH, Chun HS, Joh TH, Cho S, Conti B, Lee JW.
Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos.
J Neurosci. 1999 Jan 1;19(1):10-20.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Calingasan NY, Park LC, Calo LL, Trifiletti RR, Gandy SE, Gibson GE.
Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism.
Am J Pathol. 1998 Aug;153(2):599-610.
Full-Text on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Calingasan NY, Baker H, Sheu KF, Gibson GE.
Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency.
Exp Neurol. 1995 Jul;134(1):64-72.
Abstract on PubMed
Cho Lab
PUBLICATION: 
Journal Article
Pellegrini-Giampietro DE, Zukin RS, Bennett MV, Cho S, Pulsinelli WA.
Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.
Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10499-503. Erratum in: Proc Natl Acad Sci U S A 1993 Jan 15;90(2):780.
Full-Text on PubMed
Cho Lab
PUBLICATION: 
Journal Article
Buchan AM, Li H, Cho S, Pulsinelli WA.
Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats.
Neurosci Lett. 1991 Nov 11;132(2):255-8.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Gibson G, Toral-Barza L, Huang HM.
Cytosolic free calcium concentrations in synaptosomes during histotoxic hypoxia.
Neurochem Res. 1991 Apr;16(4):461-7.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Huang HM, Toral-Barza L, Gibson G.
Cytosolic free calcium and ATP in synaptosomes after ischemia.
Life Sci. 1991;48(15):1439-45.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Freeman GB, Gibson GE.
Selective alteration of mouse brain neurotransmitter release with age.
Neurobiol Aging. 1987 Mar-Apr;8(2):147-52.
Abstract on PubMed

Causes

Motor Recovery, Pain & Sensory Recovery, Cognitive Recovery, Vision Recovery, Stroke, Spinal Cord Injury, Neurodegenerative Diseases