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Mitochondrial Dysfunction in Neurodegeneration of Aging

June 2, 1999 to April 30, 2015
GRANT: 
Federal
Funding Status: 
Completed Project
Funding Agency: 
National Institutes of Health (NIH)
Funding Institute: 
National Institute on Aging (NIA)
Grant Number: 
P01AG014930
Published Grant: 
NIH RePORT

Goals

The proposed experiments will test whether increasing KGDHC via inhibition of TGase or via a host of other strategies would be effective therapeutic approaches in age-associated neurodegenerative diseases. Successful completion of the goals of these projects can be expected to provide new insights into neurodegenerative processes and contribute to novel approaches to ameliorating age-related neurodegenerations.

Investigators

Gary's Photo
Lab Director
Laboratory for Mitochondrial Biology and Metabolic Dysfunction in Neurodegeneration
Role: 
Principal Investigator
Raj's Photo
Chief Executive Officer
Burke Professor, Associate Dean (affiliate)
Role: 
Project Leader

Associated

Conditions & Recovery

Cognitive Recovery icon
Remember and speak clearly.
Neurodegenerative Diseases icon
Worldwide, 50 million people are living with Alzheimer's and other dementias.

Research Methods