Publications for Saravanan S. Karuppagounder, Ph.D. | Burke Neurological Institute

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Saravanan S. Karuppagounder, Ph.D.

Former Director

Spinal Cord Injury Core

Laboratory for Neural Redox Biology and Homeostatic Transcription

Former Assistant Professor of Research in Neuroscience

Weill Cornell Medicine

Publications for Saravanan S. Karuppagounder, Ph.D.

Showing 1 - 50 of 50 total

Cho Lab / Ratan Lab

PUBLICATION:

Journal Article

Amit Kumar, Saravanan S Karuppagounder, Yingxin Chen, Carlo Corona, Riki Kawaguchi, Yuyan Cheng, Mustafa Balkaya, Botir T Sagdullaev, Zhexing Wen, Charles Stuart, Sunghee Cho, Guo-Li Ming, Jürgen Tuvikene, Tõnis Timmusk, Daniel H Geschwind, Rajiv R Ratan

2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience

Neuron . 2023 Jul 11;S0896-6273(23)00472-5. doi: 10.1016/j.neuron.2023.06.013. Online ahead of print.

Full Text on Neuron

PUBLICATION:

Journal Article

Amit Kumar, Saravanan S. Karuppagounder, Yingxin Chen, Carlo Corona, Riki Kawaguchi, Yuyan Cheng, Mustafa Balkaya, Botir T. Sagdullaev, Zhexing Wen, Charles Stuart, Sunghee Cho, Guo-li Ming, Jürgen Tuvikene, Tõnis Timmusk, Daniel H. Geschwind, Rajiv R. Ratan

2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience

Science Direct 14 July 2023

Full Text on Science Direct

PUBLICATION:

Journal Article

Brian T David, Jessica J Curtin, Jennifer L Brown, Kerri Scorpio, Veena Kandaswamy, David J C Coutts, Ana Vivinetto, Paola Bianchimano, Saravanan S Karuppagounder, Mariajose Metcalfe, John W Cave, Caitlin E Hill

Temporary induction of hypoxic adaptations by preconditioning fails to enhance Schwann cell transplant survival after spinal cord injury

Glia . 2023 Mar;71(3):648-666. doi: 10.1002/glia.24302. Epub 2022 Dec 24.

Full Text on Wiley

PUBLICATION:

Journal Article

Nandini Kundu, Amit Kumar, Carlo Corona, Yingxin Chen, Sonia Seth, Saravanan S. Karuppagounder, Rajiv R. Ratan

A STING agonist preconditions against ischaemic stroke via an adaptive antiviral Type 1 interferon response

Brain Commun. 2022 May 24;4(3):fcac133. doi: 10.1093/braincomms/fcac133. eCollection 2022.

PDF on Oxford Academic

PUBLICATION:

Manuscript

Marietta Zille, Juan A Oses-Prieto, Sara R Savage, Saravanan S Karuppagounder, Yingxin Chen, Amit Kumar, John H Morris, Karl A Scheidt, Alma L Burlingame, Rajiv R Ratan

Hemin-Induced Death Models Hemorrhagic Stroke and Is a Variant of Classical Neuronal Ferroptosis

J Neurosci. 2022 Mar 9;42(10):2065-2079. doi: 10.1523/JNEUROSCI.0923-20.2021. Epub 2022 Jan 5.

Abstract on PubMed

PUBLICATION:

Manuscript

Amit Kumar, Manisha Vaish, Saravanan S Karuppagounder, Irina Gazaryan, John W Cave, Anatoly A Starkov, Elizabeth T Anderson, Sheng Zhang, John T Pinto, Austin M Rountree, Wang Wang, Ian R Sweet, Rajiv R Ratan

HIF1α stabilization in hypoxia is not oxidant-initiated

Elife. 2021 Oct 1;10:e72873. doi: 10.7554/eLife.72873.

Full-Text on Pubmed

PUBLICATION:

Journal Article

George Z Wei, Sujata Saraswat Ohri, Nicolas K Khattar, Adam W Listerman, Catherine H Doyle, Kariena R Andres , Saravanan S Karuppagounder, Rajiv R Ratan, Scott R Whittemore, Michal Hetman

Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery

PLoS One. 2021 Apr 5;16(4):e0249591. doi: 10.1371/journal.pone.0249591. eCollection 2021.

Full-Text on Pubmed

PUBLICATION:

Case Report

Michael H. Askenase, Brittany A. Goods, Hannah E. Beatty, Arthur F. Steinschneider, Sofia E. Velazquez, Artem Osherov, Margaret J. Landreneau, Shaina L. Carroll, Tho B. Tran, Victor S. Avram, Riley S. Drake, G. James Gatter, Jordan A. Massey, Saravanan S. Karuppagounder, Rajiv R. Ratan, Charles C. Matouk, Kevin N. Sheth, Wendy C. Ziai, Adrian R. Parry-Jones, Issam A. Awad, Mario Zuccarello, Richard E. Thompson, Jesse Dawson, Daniel F. Hanley, J. Christopher Love, Alex K. Shalek, Lauren H. Sansing, MISTIE III Consortium, ICHseq investigators

Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage

Science Immunology 2021 Feb 19;6(56):eabd6279. doi: 10.1126/sciimmunol.abd6279. Epub 2021 Feb 19.

Full-Text on PMC

PUBLICATION:

Review

Johannes Boltze, Jaroslaw A Aronowski, Jerome Badaut, Marion S Buckwalter, Mateo Caleo, Michael Chopp, Kunjan R Dave, Nadine Didwischus, Rick M Dijkhuizen, Thorsten R Doeppner, Jens P Dreier, Karim Fouad, Mathias Gelderblom, Karen Gertz, Dominika Golubczyk, Barbara A Gregson, Edith Hamel, Daniel F Hanley, Wolfgang Härtig, Friedhelm C Hummel, Maulana Ikhsan, Miroslaw Janowski, Jukka Jolkkonen, Saravanan S Karuppagounder, Richard F Keep, Inga K Koerte, Zaal Kokaia, Peiying Li, Fudong Liu, Ignacio Lizasoain, Peter Ludewig, Gerlinde A S Metz, Axel Montagne, Andre Obenaus, Alex Palumbo, Monica Pearl, Miguel Perez-Pinzon, Anna M Planas, Nikolaus Plesnila, Ami P Raval, Maria A Rueger, Lauren H Sansing, Farida Sohrabji, Charlotte J Stagg, R Anne Stetler, Ann M Stowe, Dandan Sun, Akihiko Taguchi, Mickael Tanter, Sabine U Vay, Raghu Vemuganti, Denis Vivien, Piotr Walczak, Jian Wang, Ye Xiong , Marietta Zille

New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases

Front Aging Neurosci. 2021 Jan 28;13:623751. doi: 10.3389/fnagi.2021.623751. eCollection 2021.

Full-Text on Pubmed

PUBLICATION:

Review

Orjon Rroji, Amit Kumar, Saravanan S Karuppagounder, Rajiv R Ratan

Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases

Neurobiol Dis. 2021 Jan;147:105145. doi: 10.1016/j.nbd.2020.105145. Epub 2020 Oct 28.

Abstract on PubMed

PUBLICATION:

Journal Article

Yujia Zhai, Yingxin Chen, Saravanan S. Karuppagounder, Amit Kumar, Nandini Kundu, Ishraq Alim, Stephanie Taylor, Craig E. Brown, Xiang Luo, Yi-Fang Li, Dawei Lian, Yang Chen, Hilda Ahnstedt, Louise D. McCullough, Rong-Rong He, Rajiv R. Ratan

Tilorone, an oral antiviral agent utilized in humans, preconditions against transient ischemia in mice

Conditioning Medicine 2020. 3(1): 1-8.

Full-Text on Conditioning Medicine

PUBLICATION:

Journal Article

Aimé P, Karuppagounder SS, Rao A, Chen Y, Burke RE, Ratan RR, Greene LA.

The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease.

Neurobiol Dis. 2020 Mar;136:104725. doi: 10.1016/j.nbd.2019.104725. Epub 2020 Jan 3.

Full-Text on Pubmed

PUBLICATION:

Journal Article

Ishraq Alim, Joseph T. Caulfield, Yingxin Chen, Vivek Swarup, Daniel H. Geschwind, Elena Ivanova, Javier Seravalli, Youxi Ai, Lauren H. Sansing, Emma J. Ste.Marie, Robert J. Hondal, Sushmita Mukherjee, John W. Cave, Botir T. Sagdullaev, Saravanan S. Karuppagounder, Rajiv R. Ratan

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

Cell. 2019 May 16;177(5):1262-1279.e25. doi: 10.1016/j.cell.2019.03.032. Epub 2019 May 2.

Abstract on CellPress

Ratan Lab / Willis Lab

PUBLICATION:

Manuscript

Marietta Zille, Amit Kumar, Nandini Kundu, Megan W. Bourassa, Victor S. C. Wong, Dianna Willis, Saravanan S. Karuppagounder and Rajiv R. Ratan

Ferroptosis in neurons and cancer cells is similar but differentially regulated by histone deacetylase inhibitors

eNeuro. 2019 Feb 15;6(1). pii: ENEURO.0263-18.2019. doi: 10.1523/ENEURO.0263-18.2019. eCollection 2019 Jan-Feb.

Full-Text on Pubmed

PUBLICATION:

Journal Article

Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA, Kumar A, Perry S, Pinto JT, Darley-Usmar V, Sanchez S, Milne GL8, Pratico D, Holman TR, Carmichael ST, Coppola G, Colbourne F, Ratan RR.

N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with PGE2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice.

Ann Neurol. 2018 Dec;84(6):854-872. doi: 10.1002/ana.25356. Epub 2018 Nov 29.

Full-Text on Pubmed

PUBLICATION:

Journal Article

Karuppagounder SS, Zhai Y, Chen Y, He R, Ratan RR.

The interferon response as a common final pathway for many preconditioning stimuli: unexpected crosstalk between hypoxic adaptation and antiviral defense.

Cond Med. 2018 Apr;1(4):143-150. Epub 2018 Jun 15.

Abstract on PubMed

PUBLICATION:

Journal Article

Zille M, Karuppagounder SS, Chen Y, Gough PJ, Bertin J, Finger J, Milner TA, Jonas EA, Ratan RR.

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis.

Zille M, Karuppagounder SS, Chen Y, Gough PJ, Bertin J, Finger J, Milner TA, Jonas EA, Ratan RR. Stroke. 2017 Apr;48(4):1033-1043. doi: 10.1161/STROKEAHA.116.015609. Epub 2017 Mar 1.

Abstract on PubMed

PUBLICATION:

Journal Article

Smirnova NA, Kaidery NA, Hushpulian DM, Rakhman II, Poloznikov AA, Tishkov VI, Karuppagounder SS, Gaisina IN, Pekcec A, Leyen KV, Kazakov SV, Yang L, Thomas B, Ratan RR, Gazaryan IG.

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease.

Aging Dis. 2016 Dec 1;7(6):745-762. doi: 10.14336/AD.2016.0505. eCollection 2016 Dec.

Full-Text on PubMed

PUBLICATION:

Journal Article

Sleiman SF, Henry J, Al-Haddad R, El Hayek L, Abou Haidar E, Stringer T, Ulja D, Karuppagounder SS, Holson EB, Ratan RR, Ninan I, Chao MV.

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate.

Elife. 2016 Jun 2;5. doi:pii: e15092. 10.7554/eLife.15092.

Full-Text on PubMed

PUBLICATION:

Journal Article

Neitemeier S, Dolga AM, Honrath B, Karuppagounder SS, Alim I, Ratan RR, Culmsee C.

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis.

Cell Death Dis. 2016 May 5;7:e2214. doi: 10.1038/cddis.2016.107.

Abstract on PubMed

Cho Lab / Ratan Lab

PUBLICATION:

Journal Article

Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Sci Transl Med. 2016 Mar 2;8(328):328ra29. doi: 10.1126/scitranslmed.aac6008.

Abstract on PubMed

PUBLICATION:

Review

Karuppagounder SS, Kumar A, Shao DS, Zille M, Bourassa MW, Caulfield JT, Alim I, Ratan RR.

Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases.

Brain Res. 2015 Dec 2;1628(Pt B):273-87. doi: 10.1016/j.brainres.2015.07.030. Review.

Abstract on PubMed

PUBLICATION:

Journal Article

Sleiman SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J, Wagner FF, Basso M, Coppola G, Pinto JT, Holson EB, Ratan RR.

Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition.

J Neurosci. 2014 Oct 22;34(43):14328-37. doi: 10.1523/JNEUROSCI.1010-14.2014. Erratum in: J Neurosci. 2015 Jan 7;35(1):438.

Full-Text on PubMed

PUBLICATION:

Journal Article

Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, Andersen JK, Ratan RR.

Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.

Antioxid Redox Signal. 2015 Jan 10;22(2):121-34. doi: 10.1089/ars.2013.5595.

Full-Text on PubMed

PUBLICATION:

Review

Elder J, Cortes M, Rykman A, Hill J, Karuppagounder S, Edwards D, Ratan RR.

The epigenetics of stroke recovery and rehabilitation: from polycomb to histone deacetylases.

Neurotherapeutics. 2013 Oct;10(4):808-16. doi: 10.1007/s13311-013-0224-3. Review.

Full-Text on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Basso M, Sleiman SF, Ma TC, Speer RE, Smirnova NA, Gazaryan IG, Ratan RR.

In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.

J Neurosci Res. 2013 Aug;91(8):1066-75. doi: 10.1002/jnr.23204.

Full-Text on PubMed

PUBLICATION:

Journal Article

Madathil SK, Karuppagounder SS, Mohanakumar KP.

Sodium salicylate protects against rotenone-induced parkinsonism in rats.

Synapse. 2013 Aug;67(8):502-14. doi: 10.1002/syn.21658.

Abstract on PubMed

PUBLICATION:

Review

Speer RE, Karuppagounder SS, Basso M, Sleiman SF, Kumar A, Brand D, Smirnova N, Gazaryan I, Khim SJ, Ratan RR.

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by antioxidant metal chelators: From ferroptosis to stroke.

Free Radic Biol Med. 2013 Sep;62:26-36. doi: 10.1016/j.freeradbiomed.2013.01.026. Review.

Full-Text on PubMed

PUBLICATION:

Journal Article

Sleiman SF, Berlin J, Basso M, Karuppagounder SS, Rohr J, Ratan RR.

Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration.

Pharmaceuticals (Basel). 2011 Aug 22;4(8):1183-1195.

Full-Text on PubMed

PUBLICATION:

Review

Karuppagounder SS, Ratan RR.

Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?

J Cereb Blood Flow Metab. 2012 Jul;32(7):1347-61. doi: 10.1038/jcbfm.2012.28. Review.

Full-Text on PubMed

PUBLICATION:

Review

Gibson GE, Karuppagounder SS, Shi Q.

Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimer's disease.

Ann N Y Acad Sci. 2008 Dec;1147:221-32. doi: 10.1196/annals.1427.038. Review.

Full-Text on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE.

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.

Neurochem Int. 2009 Feb;54(2):111-8. doi: 10.1016/j.neuint.2008.10.008.

Full-Text on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Xu H, Shi Q, Chen LH, Pedrini S, Pechman D, Baker H, Beal MF, Gandy SE, Gibson GE.

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model.

Neurobiol Aging. 2009 Oct;30(10):1587-600. doi: 10.1016/j.neurobiolaging.2007.12.013.

Full-Text on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Xu H, Pechman D, Chen LH, DeGiorgio LA, Gibson GE.

Translocation of amyloid precursor protein C-terminal fragment(s) to the nucleus precedes neuronal death due to thiamine deficiency-induced mild impairment of oxidative metabolism.

Neurochem Res. 2008 Jul;33(7):1365-72. doi: 10.1007/s11064-008-9594-z.

Full-Text on PubMed

PUBLICATION:

Journal Article

Thomas B, Saravanan KS, Mohanakumar KP.

In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazole.

Neurochem Int. 2008 May;52(6):990-1001. doi: 10.1016/j.neuint.2007.10.012.

Abstract on PubMed

PUBLICATION:

Book Chapter

Karuppagounder SS, Gibson GE.

Metabolic Encephalopathy; Thiamine Deficiency: A Model of Metabolic Encephalopathy and of Selective Neuronal Vulnerability

McCandless DW, editor. New York: Springer; 2008. Thiamine Deficiency: A Model of Metabolic Encephalopathy and of Selective Neuronal Vulnerability; p.235-260.

Book on Springer

PUBLICATION:

Journal Article

Banerjee R, Saravanan KS, Thomas B, Sindhu KM, Mohanakumar KP.

Evidence for hydroxyl radical scavenging action of nitric oxide donors in the protection against 1-methyl-4-phenylpyridinium-induced neurotoxicity in rats.

Neurochem Res. 2008 Jun;33(6):985-95.

Abstract on PubMed

PUBLICATION:

Journal Article

Senthilkumar KS, Saravanan KS, Chandra G, Sindhu KM, Jayakrishnan A, Mohanakumar KP.

Unilateral implantation of dopamine-loaded biodegradable hydrogel in the striatum attenuates motor abnormalities in the 6-hydroxydopamine model of hemi-parkinsonism.

Behav Brain Res. 2007 Nov 22;184(1):11-8.

Abstract on PubMed

PUBLICATION:

Journal Article

Shi Q, Karuppagounder SS, Xu H, Pechman D, Chen H, Gibson GE.

Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.

Neurochem Int. 2007 Jun;50(7-8):921-31.

Full-Text on PubMed

PUBLICATION:

Journal Article

Banerjee R, Sreetama S, Saravanan KS, Dey SN, Mohanakumar KP.

Apoptotic mode of cell death in substantia nigra following intranigral infusion of the parkinsonian neurotoxin, MPP+ in Sprague-Dawley rats: cellular, molecular and ultrastructural evidences.

Neurochem Res. 2007 Jul;32(7):1238-47.

Abstract on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Shi Q, Xu H, Gibson GE.

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism.

Neurobiol Dis. 2007 May;26(2):353-62.

Full-Text on PubMed

PUBLICATION:

Journal Article

Saravanan KS, Sindhu KM, Mohanakumar KP.

Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model.

J Pineal Res. 2007 Apr;42(3):247-53.

Abstract on PubMed

PUBLICATION:

Journal Article

Banerjee R, Sreetama S, Saravanan KS, Chandra G, Nath De S, Mohanakumar KP.

Intrastriatal infusion of the Parkinsonian neurotoxin, MPP(+), induces damage of striatal cell nuclei in Sprague-Dawley rats.

J Chem Neuroanat. 2006 Dec;32(2-4):90-100.

Abstract on PubMed

PUBLICATION:

Journal Article

Sindhu KM, Banerjee R, Senthilkumar KS, Saravanan KS, Raju BC, Rao JM, Mohanakumar KP.

Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine.

Pharmacol Biochem Behav. 2006 Jun;84(2):321-9.

Abstract on PubMed

PUBLICATION:

Journal Article

Saravanan KS, Sindhu KM, Senthilkumar KS, Mohanakumar KP.

L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.

Neurochem Int. 2006 Jul;49(1):28-40.

Abstract on PubMed

PUBLICATION:

Journal Article

Sindhu KM, Saravanan KS, Mohanakumar KP.

Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion.

Brain Res. 2005 Jul 27;1051(1-2):25-34.

Abstract on PubMed

PUBLICATION:

Journal Article

Saravanan KS, Sindhu KM, Mohanakumar KP.

Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease.

Brain Res. 2005 Jul 12;1049(2):147-55.

Abstract on PubMed

PUBLICATION:

Journal Article

Ke ZJ, Calingasan NY, Karuppagounder SS, DeGiorgio LA, Volpe BT, Gibson GE.

CD40L deletion delays neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism.

J Neuroimmunol. 2005 Jul;164(1-2):85-92.

Abstract on PubMed

PUBLICATION:

Journal Article

Mehta H, Saravanan KS, Mohanakumar KP.

Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.

Behav Brain Res. 2003 Oct 17;145(1-2):31-6.

Abstract on PubMed

PUBLICATION:

Journal Article

Sairam K, Saravanan KS, Banerjee R, Mohanakumar KP.

Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.

Brain Res. 2003 Mar 21;966(2):245-52.

Abstract on PubMed