Willis Lab Publications | Burke Neurological Institute

Ribosomal S6 kinases determine intrinsic axonal regeneration capacity

PUBLICATION:

Other (Non-Standard Citation)

Wilfredo Mellado, Dianna E Willis

PLoS Biol . 2023 Apr 21;21(4):e3002094. doi: 10.1371/journal.pbio.3002094. eCollection 2023 Apr.

Full Text on PMC

An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model

PUBLICATION:

Journal Article

Gareth R Tibbs, Rajendra Uprety, J David Warren, Nicole P Beyer, Rebecca L Joyce, Matthew A Ferrer, Wilfredo Mellado, Victor S C Wong, David C Goldberg, Melanie W Cohen, Christopher J Costa, Zhucui Li, Guoan Zhang, Noah E Dephoure, Dipti N Barman, Delin Sun, Helgi I Ingólfsson, Anthony A Sauve, Dianna E Willis, Peter A Goldstein

Br J Anaesth . 2023 Aug 9;S0007-0912(23)00375-6. doi: 10.1016/j.bja.2023.06.067. Online ahead of print.

Full Text on BJA

Nicotinamide Riboside Improves Enteric Neuropathy in Streptozocin-Induced Diabetic Rats Through Myenteric Plexus Neuroprotection

PUBLICATION:

Journal Article

Christopher J Costa, Melanie W Cohen, David C Goldberg, Wilfredo Mellado, Dianna E Willis

Dig Dis Sci . 2023 Jul;68(7):2963-2974. doi: 10.1007/s10620-023-07913-5. Epub 2023 Mar 15.

Full Text on Springer

Targeting Affective Mood Disorders With Ketamine to Prevent Chronic Postsurgical Pain

PUBLICATION:

Review

Dianna E Willis, Peter A Goldstein

Front Pain Res (Lausanne). 2022 Jun 27;3:872696. doi: 10.3389/fpain.2022.872696. eCollection 2022.

G-Quadruplex Regulation of Neural Gene Expression

PUBLICATION:

Review

John W Cave, Dianna E Willis

FEBS J. 2022 Jun;289(12):3284-3303. doi: 10.1111/febs.15900. Epub 2021 May 10.

Editorial: Pathways and Processes Underpinning Axonal Biology and Pathobiology

PUBLICATION:

Opinion Article

Pabitra K Sahoo, Dianna E Willis, James N Sleigh

Front Mol Neurosci. 2022 Mar 23;15:883244. doi: 10.3389/fnmol.2022.883244. eCollection 2022.

Full-Text on PMC

Failure to Upregulate the RNA Binding Protein ZBP After Injury Leads to Impaired Regeneration in a Rodent Model of Diabetic Peripheral Neuropathy

PUBLICATION:

Journal Article

James I. Jones, Christopher J. Costa, Caitlin Cooney, David C. Goldberg, Matthew Ponticiello, Melanie W. Cohen, Wilfredo Mellado, Thong C. Ma, and Dianna E. Willis

Front Mol Neurosci. 2021 Dec 7;14:728163. doi: 10.3389/fnmol.2021.728163. eCollection 2021.

Full-Text on Frontiers

Stressing out translation

PUBLICATION:

Opinion Article

Wilfredo Mellado, Dianna E Willis

Science. 2021 Sep 3;373(6559):1089-1090. doi: 10.1126/science.abk3261. Epub 2021 Sep 1.

Abstract on Science

Prusky Lab / Willis Lab

PUBLICATION:

Journal Article

Picci C, Wong VSC, Costa CJ, McKinnon MC, Goldberg DC, Swift M, Alam NM, Prusky GT, Shen S, Kozikowski AP, Willis DE, Langley B.

HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice.

Exp Neurol. 2020 Jun;328:113281. doi: 10.1016/j.expneurol.2020.113281. Epub 2020 Mar 5.

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.

PUBLICATION:

Journal Article

Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL.

J Cell Biol. 2019 Jun 3;218(6):1871-1890. doi: 10.1083/jcb.201702187. Epub 2019 May 8.

Full-Text on on PubMed

Ratan Lab / Willis Lab

PUBLICATION:

Manuscript

Marietta Zille, Amit Kumar, Nandini Kundu, Megan W. Bourassa, Victor S. C. Wong, Dianna Willis, Saravanan S. Karuppagounder and Rajiv R. Ratan

Ferroptosis in neurons and cancer cells is similar but differentially regulated by histone deacetylase inhibitors

eNeuro. 2019 Feb 15;6(1). pii: ENEURO.0263-18.2019. doi: 10.1523/ENEURO.0263-18.2019. eCollection 2019 Jan-Feb.

Full-Text on Pubmed

Semaphorin3A Induces Acute Changes in Membrane Excitability in Spiral Ganglion Neurons In Vitro.

PUBLICATION:

Manuscript

Wong VSC, Meadows M, Goldberg D, Willis DE.

Eur J Neurosci . 2019 Jul;50(1):1741-1758. doi: 10.1111/ejn.14360. Epub 2019 Feb 25.

Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

PUBLICATION:

Journal Article

Gershoni-Emek N, Altman T, Ionescu A, Costa CJ, Gradus-Pery T, Willis DE, Perlson E.

Front Mol Neurosci. 2018 Sep 5;11:311. doi: 10.3389/fnmol.2018.00311. eCollection 2018.

Alpha-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin Associated Glycoprotein.

PUBLICATION:

Journal Article

Wong VSC, Picci C, Swift M, Levinson M, Willis D, Langley B

eNeuro. 2018 Feb 28;5(1). pii: ENEURO.0240-17.2018. doi: 10.1523/ENEURO.0240-17.2018. eCollection 2018 Jan-Feb.

Full-Text on Pubmed

To the End of the Line: Axonal mRNA transport and local translation in health and neurodegenerative disease.

PUBLICATION:

Review

Costa CJ, Willis DE.

Dev Neurobiol. 2018 Mar;78(3):209-220. doi: 10.1002/dneu.22555. Epub 2017 Nov 13.

ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.

PUBLICATION:

Journal Article

Rotem N, Magen I, Ionescu A, Gershoni-Emek N, Altman T, Costa CJ, Gradus T, Pasmanik-Chor M, Willis DE, Ben-Dov IZ, Hornstein E, Perlson E.

Sci Rep. 2017 Mar 16;7:44500. doi: 10.1038/srep44500.

Neural Circuits Catch Fire.

PUBLICATION:

Journal Article

Carmel JB, Willis DE.

Neurotherapeutics. 2016 Apr;13(2):261-3. doi: 10.1007/s13311-016-0428-4. No abstract available.

Selective repression of gene expression in neuropathic pain by the neuron-restrictive silencing factor/repressor element-1 silencing transcription (NRSF/REST).

PUBLICATION:

Review

Willis DE, Wang M, Brown E, Fones L, Cave JW.

Neurosci Lett. 2016 Jun 20;625:20-5. doi: 10.1016/j.neulet.2015.12.003. Review.

Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration.

PUBLICATION:

Journal Article

Brochier C, Jones JI, Willis DE, Langley B.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15220-5. doi: 10.1073/pnas.1509754112.

Transcriptomic Approaches to Neural Repair.

PUBLICATION:

Review

Dulin JN, Antunes-Martins A, Chandran V, Costigan M, Lerch JK, Willis DE, Tuszynski MH.

J Neurosci. 2015 Oct 14;35(41):13860-7. doi: 10.1523/JNEUROSCI.2599-15.2015. Review.

What makes a RAG regeneration associated?

PUBLICATION:

Review

Ma TC, Willis DE.

Front Mol Neurosci. 2015 Aug 7;8:43. doi: 10.3389/fnmol.2015.00043. Review.

A brief review of recent Charcot-Marie-Tooth research and priorities.

PUBLICATION:

Review

Ekins S, Litterman NK, Arnold RJ, Burgess RW, Freundlich JS, Gray SJ, Higgins JJ, Langley B, Willis DE, Notterpek L, Pleasure D, Sereda MW, Moore A.

F1000Res. 2015 Feb 26;4:53. doi: 10.12688/f1000research.6160.1. Review.

cAMP-responsive element-binding protein (CREB) and cAMP co-regulate activator protein 1 (AP1)-dependent regeneration-associated gene expression and neurite growth.

Ratan Lab / Willis Lab

PUBLICATION:

Journal Article

Ma TC, Barco A, Ratan RR, Willis DE.

J Biol Chem. 2014 Nov 21;289(47):32914-25. doi: 10.1074/jbc.M114.582460.

A screen for inducers of p21(waf1/cip1) identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties.

Willis Lab / Ratan Lab

PUBLICATION:

Journal Article

Ma TC, Langley B, Ko B, Wei N, Gazaryan IG, Zareen N, Yamashiro DJ, Willis DE, Ratan RR.

Neurobiol Dis. 2013 Jan;49:13-21. doi: 10.1016/j.nbd.2012.08.016.

Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.

Willis Lab / Cho Lab / Ratan Lab

PUBLICATION:

Journal Article

Basso M, Berlin J, Xia L, Sleiman SF, Ko B, Haskew-Layton R, Kim E, Antonyak MA, Cerione RA, Iismaa SE, Willis D, Cho S, Ratan RR.

J Neurosci. 2012 May 9;32(19):6561-9. doi: 10.1523/JNEUROSCI.3353-11.2012. Erratum in: J Neurosci. 2012 Aug 8;32(32):11157.

Lysophosphatidic acid differentially regulates axonal mRNA translation through 5'UTR elements.

Ratan Lab / Willis Lab

PUBLICATION:

Journal Article

Vuppalanchi D, Merianda TT, Donnelly C, Pacheco A, Williams G, Yoo S, Ratan RR, Willis DE, Twiss JL.

Mol Cell Neurosci. 2012 Jun;50(2):136-46. doi: 10.1016/j.mcn.2012.04.001.

Axonal transcription factors signal retrogradely in lesioned peripheral nerve.

PUBLICATION:

Journal Article

Ben-Yaakov K, Dagan SY, Segal-Ruder Y, Shalem O, Vuppalanchi D, Willis DE, Yudin D, Rishal I, Rother F, Bader M, Blesch A, Pilpel Y, Twiss JL, Fainzilber M.

EMBO J. 2012 Mar 21;31(6):1350-63. doi: 10.1038/emboj.2011.494.

Axonal Localization of transgene mRNA in mature PNS and CNS neurons.

PUBLICATION:

Journal Article

Willis DE, Xu M, Donnelly CJ, Tep C, Kendall M, Erenstheyn M, English AW, Schanen NC, Kirn-Safran CB, Yoon SO, Bassell GJ, Twiss JL.

J Neurosci. 2011 Oct 12;31(41):14481-7. doi: 10.1523/JNEUROSCI.2950-11.2011.

Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity.

PUBLICATION:

Journal Article

Donnelly CJ, Willis DE, Xu M, Tep C, Jiang C, Yoo S, Schanen NC, Kirn-Safran CB, van Minnen J, English A, Yoon SO, Bassell GJ, Twiss JL.

EMBO J. 2011 Sep 30;30(22):4665-77. doi: 10.1038/emboj.2011.347.

Profiling axonal mRNA transport.

PUBLICATION:

Journal Article

Willis DE, Twiss JL.

Methods Mol Biol. 2011;714:335-52. doi: 10.1007/978-1-61779-005-8_21.

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.

PUBLICATION:

Journal Article

Gumy LF, Yeo GS, Tung YC, Zivraj KH, Willis D, Coppola G, Lam BY, Twiss JL, Holt CE, Fawcett JW.

RNA. 2011 Jan;17(1):85-98. doi: 10.1261/rna.2386111.

Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.

PUBLICATION:

Journal Article

Vuppalanchi D, Coleman J, Yoo S, Merianda TT, Yadhati AG, Hossain J, Blesch A, Willis DE, Twiss JL.

J Biol Chem. 2010 Jun 4;285(23):18025-38. doi: 10.1074/jbc.M109.061333.

Regulation of protein levels in subcellular domains through mRNA transport and localized translation.

PUBLICATION:

Journal Article

Willis DE, Twiss JL.

Mol Cell Proteomics. 2010 May;9(5):952-62. doi: 10.1074/mcp.R900005-MCP200.

A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway.

Willis Lab / Ratan Lab

PUBLICATION:

Journal Article

Ma TC, Campana A, Lange PS, Lee HH, Banerjee K, Bryson JB, Mahishi L, Alam S, Giger RJ, Barnes S, Morris SM Jr, Willis DE, Twiss JL, Filbin MT, Ratan RR.

J Neurosci. 2010 Jan 13;30(2):739-48. doi: 10.1523/JNEUROSCI.5266-09.2010.

HDAC6 is a target for protection and regeneration following injury in the nervous system.

Willis Lab / Ratan Lab

PUBLICATION:

Journal Article

Rivieccio MA, Brochier C, Willis DE, Walker BA, D'Annibale MA, McLaughlin K, Siddiq A, Kozikowski AP, Jaffrey SR, Twiss JL, Ratan RR, Langley B.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19599-604. doi: 10.1073/pnas.0907935106.

Regulation of mRNA transport and translation in axons.

PUBLICATION:

Review

Vuppalanchi D, Willis DE, Twiss JL.

Results Probl Cell Differ. 2009;48:193-224. doi: 10.1007/400_2009_16. Review.

Locally synthesized calcitonin gene-related Peptide has a critical role in peripheral nerve regeneration.

PUBLICATION:

Journal Article

Toth CC, Willis D, Twiss JL, Walsh S, Martinez JA, Liu WQ, Midha R, Zochodne DW.

J Neuropathol Exp Neurol. 2009 Mar;68(3):326-37. doi: 10.1097/NEN.0b013e31819ac71b.

A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins.

PUBLICATION:

Journal Article

Merianda TT, Lin AC, Lam JS, Vuppalanchi D, Willis DE, Karin N, Holt CE, Twiss JL.

Mol Cell Neurosci. 2009 Feb;40(2):128-42. doi: 10.1016/j.mcn.2008.09.008.

Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve.

PUBLICATION:

Journal Article

Yudin D, Hanz S, Yoo S, Iavnilovitch E, Willis D, Gradus T, Vuppalanchi D, Segal-Ruder Y, Ben-Yaakov K, Hieda M, Yoneda Y, Twiss JL, Fainzilber M.

Neuron. 2008 Jul 31;59(2):241-52. doi: 10.1016/j.neuron.2008.05.029.

Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.

PUBLICATION:

Journal Article

Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL.

J Cell Biol. 2007 Sep 10;178(6):965-80.

Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.

PUBLICATION:

Journal Article

van Niekerk EA, Willis DE, Chang JH, Reumann K, Heise T, Twiss JL.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12913-8.

RNA transport and localized protein synthesis in neurological disorders and neural repair.

PUBLICATION:

Review

Wang W, van Niekerk E, Willis DE, Twiss JL.

Dev Neurobiol. 2007 Aug;67(9):1166-82. Review.

The evolving roles of axonally synthesized proteins in regeneration.

PUBLICATION:

Review

Willis DE, Twiss JL.

Curr Opin Neurobiol. 2006 Feb;16(1):111-8. Review.

Transcription of brain creatine kinase in U87-MG glioblastoma is modulated by factor AP2.

PUBLICATION:

Journal Article

Willis D, Zhang Y, Molloy GR.

Biochim Biophys Acta. 2005 Apr 5;1728(1-2):18-33.

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.

PUBLICATION:

Journal Article

Willis D, Li KW, Zheng JQ, Chang JH, Smit AB, Kelly T, Merianda TT, Sylvester J, van Minnen J, Twiss JL.

J Neurosci. 2005 Jan 26;25(4):778-91. Erratum in: J Neurosci. 2010 Nov 10;30(45):np. Smit, August [corrected to Smit, August B].

Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells.

PUBLICATION:

Journal Article

Rajasekaran SA, Gopal J, Willis D, Espineda C, Twiss JL, Rajasekaran AK.

Mol Biol Cell. 2004 Jul;15(7):3224-32.

Expression of creatine kinase isoenzyme genes during postnatal development of rat brain cerebrum: evidence for posttranscriptional regulation.

PUBLICATION:

Journal Article

Shen W, Willis D, Zhang Y, Molloy GR.

Dev Neurosci. 2003 Nov-Dec;25(6):421-35.

Axoplasmic importins enable retrograde injury signaling in lesioned nerve.

PUBLICATION:

Journal Article

Hanz S, Perlson E, Willis D, Zheng JQ, Massarwa R, Huerta JJ, Koltzenburg M, Kohler M, van-Minnen J, Twiss JL, Fainzilber M.

Neuron. 2003 Dec 18;40(6):1095-104.

Expression of creatine kinase isoenzyme genes during postnatal development of rat brain cerebellum: evidence for transcriptional regulation.

PUBLICATION:

Journal Article

Shen W, Willis D, Zhang Y, Schlattner U, Wallimann T, Molloy GR.

Biochem J. 2002 Oct 15;367(Pt 2):369-80.

Conditions providing enhanced transfection efficiency in rat pheochromocytoma PC12 cells permit analysis of the activity of the far-upstream and proximal promoter of the brain creatine kinase gene.

PUBLICATION:

Journal Article

Willis D, Parameswaran B, Shen W, Molloy GR.

J Neurosci Methods. 1999 Oct 15;92(1-2):3-13.