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Genetics

Impact

PUBLICATION:

Journal Article

McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, Geschwind DH, Ryu H, Xia L, Iismaa SE, Pallos J, Pasternack R, Hils M, Fan J, Raymond LA, Marsh JL, Thompson LM, Ratan RR.

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

EMBO Mol Med. 2010 Sep;2(9):349-70. doi: 10.1002/emmm.201000084.

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PUBLICATION:

Review

Gibson GE, Shi Q.

A mitocentric view of Alzheimer's disease suggests multi-faceted treatments.

J Alzheimers Dis. 2010;20 Suppl 2:S591-607. doi: 10.3233/JAD-2010-100336. Review.

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Journal Article

Yang L, Shi Q, Ho DJ, Starkov AA, Wille EJ, Xu H, Chen HL, Zhang S, Stack CM, Calingasan NY, Gibson GE, Beal MF.

Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins.

Neurobiol Dis. 2009 Nov;36(2):320-30. doi: 10.1016/j.nbd.2009.07.023.

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PUBLICATION:

Journal Article

Lu Q, Ivanova E, Pan ZH.

Characterization of green fluorescent protein-expressing retinal cone bipolar cells in a 5-hydroxytryptamine receptor 2a transgenic mouse line.

Neuroscience. 2009 Oct 6;163(2):662-8. doi: 10.1016/j.neuroscience.2009.07.002.

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Journal Article

Kim E, Tolhurst AT, Qin LY, Chen XY, Febbraio M, Cho S

CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury

J Neurosci. 2008 Apr 30;28(18):4661-70. doi: 10.1523/JNEUROSCI.0982-08.2008.

Abstract on PubMed

PUBLICATION:

Journal Article

Karuppagounder SS, Xu H, Pechman D, Chen LH, DeGiorgio LA, Gibson GE.

Translocation of amyloid precursor protein C-terminal fragment(s) to the nucleus precedes neuronal death due to thiamine deficiency-induced mild impairment of oxidative metabolism.

Neurochem Res. 2008 Jul;33(7):1365-72. doi: 10.1007/s11064-008-9594-z.

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Journal Article

van Niekerk EA, Willis DE, Chang JH, Reumann K, Heise T, Twiss JL.

Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12913-8.

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PUBLICATION:

Review

Wang W, van Niekerk E, Willis DE, Twiss JL.

RNA transport and localized protein synthesis in neurological disorders and neural repair.

Dev Neurobiol. 2007 Aug;67(9):1166-82. Review.

Abstract on PubMed

PUBLICATION:

Journal Article

Shi Q, Karuppagounder SS, Xu H, Pechman D, Chen H, Gibson GE.

Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.

Neurochem Int. 2007 Jun;50(7-8):921-31.

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PUBLICATION:

Journal Article

Karuppagounder SS, Shi Q, Xu H, Gibson GE.

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism.

Neurobiol Dis. 2007 May;26(2):353-62.

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