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Genetics
Genetics
Impact
Cho Lab
GRANT:
Non-Federal
December 15, 2015
to
December 15, 2016
Effect of CD36 Inhibition to Control Visceral Obesity/Insulin Resistance in BDNF Val66met Carrier
Funding Status:
Completed Project
Sanofi iAward
Investigators:
Sunghee Cho, Ph.D.
Principal Investigator
Ratan Lab
/
Cho Lab
PUBLICATION:
Journal Article
Kim E, Woo MS, Qin L, Ma T, Beltran CD, Bao Y, Bailey JA, Corbett D, Ratan RR, Lahiri DK, Cho S.
Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke
J Neurosci. 2015 Nov 11;35(45):15113-26. doi: 10.1523/JNEUROSCI.2890-15.2015.
Abstract on PubMed
PUBLICATION:
Journal Article
Ivanova E, Yee CW, Baldoni R Jr, Sagdullaev BT.
Aberrant activity in retinal degeneration impairs central visual processing and relies on Cx36-containing gap junctions.
Exp Eye Res. 2016 Sep;150:81-9. doi: 10.1016/j.exer.2015.05.013. Epub 2015 May 22.
Full-Text Article on PubMed
Ratan Lab
PRESENTATION:
Invited Speaker
April 8, 2015
Harnessing the Adaptive Genetic Responses to Hypoxia to Protect & Repair the Brain Following Stroke
Venue:
Mercy College, Department of Natural Sciences, Dobbs Ferry, NY
Featured Researchers:
Rajiv R. Ratan, M.D., Ph.D.
Ratan Lab
PUBLICATION:
Review
Bourassa MW, Ratan RR.
The interplay between microRNAs and histone deacetylases in neurological diseases.
Neurochem Int. 2014 Nov;77:33-9. doi: 10.1016/j.neuint.2014.03.012. Review.
Full-Text on PubMed
Ratan Lab
PUBLICATION:
Review
Kumar A, Vaish M, Ratan RR.
Transcriptional dysregulation in Huntington's disease: a failure of adaptive transcriptional homeostasis.
Drug Discov Today. 2014 Jul;19(7):956-62. doi: 10.1016/j.drudis.2014.03.016. Review.
Full-Text on PubMed
Ratan Lab
/
Cho Lab
PUBLICATION:
Journal Article
Qin L, Jing D, Parauda S, Carmel J, Ratan RR, Lee FS, Cho S
An adaptive role for BDNF Val66Met polymorphism in motor recovery in chronic stroke
J Neurosci. 2014 Feb 12;34(7):2493-502. doi: 10.1523/JNEUROSCI.4140-13.2014.
Abstract on PubMed
PUBLICATION:
Review
Langley B, Sauve A.
Sirtuin deacetylases as therapeutic targets in the nervous system.
Neurotherapeutics. 2013 Oct;10(4):605-20. doi: 10.1007/s13311-013-0214-5. Review.
Full-Text on PubMed
Ratan Lab
PUBLICATION:
Journal Article
Brochier C, Dennis G, Rivieccio MA, McLaughlin K, Coppola G, Ratan RR, Langley B.
Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.
J Neurosci. 2013 May 15;33(20):8621-32. doi: 10.1523/JNEUROSCI.5214-12.2013.
Abstract on PubMed
Gibson Lab
PUBLICATION:
Journal Article
Kiss G, Konrad C, Doczi J, Starkov AA, Kawamata H, Manfredi G, Zhang SF, Gibson GE, Beal MF, Adam-Vizi V, Chinopoulos C.
The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.
FASEB J. 2013 Jun;27(6):2392-406. doi: 10.1096/fj.12-220202.
Full-Text on PubMed
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Causes
Motor Recovery
,
Pain & Sensory Recovery
,
Vision Recovery
,
Neurodegenerative Diseases
,
Retinal Degenerative Diseases