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Molecular Studies

Impact

Willis Lab
PUBLICATION: 
Review
Vuppalanchi D, Willis DE, Twiss JL.
Regulation of mRNA transport and translation in axons.
Results Probl Cell Differ. 2009;48:193-224. doi: 10.1007/400_2009_16. Review.
Abstract on PubMed
Cho Lab
PUBLICATION: 
Review
Cho S, Kim E.
CD36: a multi-modal target for acute stroke therapy.
J Neurochem. 2009 May;109 Suppl 1:126-32. doi: 10.1111/j.1471-4159.2009.05801.x. Review.
Full-Text on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Shi Q, Risa Ø, Sonnewald U, Gibson GE.
Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis.
J Neurochem. 2009 May;109 Suppl 1:214-21. doi: 10.1111/j.1471-4159.2009.05955.x.
Full-Text on PubMed
Cho Lab
PUBLICATION: 
Journal Article
Kim E, Tolhurst AT, Qin LY, Chen XY, Febbraio M, Cho S
CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury
J Neurosci. 2008 Apr 30;28(18):4661-70. doi: 10.1523/JNEUROSCI.0982-08.2008.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Shi Q, Xu H, Kleinman WA, Gibson GE.
Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.
Biochim Biophys Acta. 2008 Apr;1782(4):229-38. doi: 10.1016/j.bbadis.2007.12.008.
Full-Text on PubMed
Gibson Lab
PUBLICATION: 
Review
Bunik VI, Schloss JV, Pinto JT, Gibson GE, Cooper AJ.
Enzyme-catalyzed side reactions with molecular oxygen may contribute to cell signaling and neurodegenerative diseases.
Neurochem Res. 2007 Apr-May;32(4-5):871-91. Review.
Abstract on PubMed
Cho Lab
PUBLICATION: 
Journal Article
Cho S, Szeto HH, Kim E, Kim H, Tolhurst AT, Pinto JT.
A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36.
J Biol Chem. 2007 Feb 16;282(7):4634-42. Epub 2006 Dec 18.
Abstract on PubMed
Cho Lab
GRANT: 
Federal
February 15, 2006 to June 30, 2015
The Role of CD36 in Ischemic Inflammation and Injury
Funding Status: 
Completed Project
National Institutes of Health (NIH)
National Heart Lung and Blood Institute (NHLBI)
Grant Number: 
R01HL082511
Investigators: 
Sunghee Cho, Ph.D.
Principal Investigator
Gibson Lab
PUBLICATION: 
Journal Article
Murphy EJ, Huang HM, Cowburn RF, Lannfelt L, Gibson GE.
Phospholipid mass is increased in fibroblasts bearing the Swedish amyloid precursor mutation.
Brain Res Bull. 2006 Mar 15;69(1):79-85.
Abstract on PubMed
Gibson Lab
PUBLICATION: 
Journal Article
Waagepetersen HS, Hansen GH, Fenger K, Lindsay JG, Gibson G, Schousboe A.
Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase.
Glia. 2006 Jan 15;53(2):225-31.
Abstract on PubMed

Causes

Motor Recovery, Pain & Sensory Recovery, Stroke, Spinal Cord Injury, Cognitive Recovery, Neurodegenerative Diseases, Vision Recovery, Retinal Degenerative Diseases