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Molecular Studies

Impact

Ratan Lab
PUBLICATION: 
Review
Karuppagounder SS, Ratan RR.
Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?
J Cereb Blood Flow Metab. 2012 Jul;32(7):1347-61. doi: 10.1038/jcbfm.2012.28. Review.
Full-Text on PubMed
Ratan Lab
GRANT: 
Non-Federal
March 1, 2012 to December 31, 2014
Epigenetic Predictors of Stroke Recovery
Funding Status: 
Completed Project
Dana Foundation
Grant Number: 
08121738
Investigators: 
Rajiv R. Ratan, M.D., Ph.D.
Principal Investigator
Andrew M. Goldfine, M.D.
Principal Investigator
Gibson Lab
PUBLICATION: 
Journal Article
Gibson GE, Chen HL, Xu H, Qiu L, Xu Z, Denton TT, Shi Q.
Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.
Neurobiol Aging. 2012 Jun;33(6):1121.e13-24. doi: 10.1016/j.neurobiolaging.2011.11.003.
Full-Text on PubMed
GRANT: 
Federal
June 16, 2011 to May 31, 2016
Plasticity in the Aging Olfactory System
Funding Status: 
Completed Project
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Grant Number: 
R01DC008955
Investigators: 
John W. Cave, Ph.D.
Principal Investigator
Harriet Baker, Ph.D.
Co-Investigator
Willis Lab
GRANT: 
Federal
April 1, 2011 to February 29, 2016
HDAC6: A Target for Regeneration Following Injury in the Nervous System
Funding Status: 
Completed Project
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Grant Number: 
R01NS071056
Investigators: 
Brett C. Langley, Ph.D.
Principal Investigator
Dianna E. Willis, Ph.D.
Co-Investigator
PUBLICATION: 
Journal Article
Newbern JM, Li X, Shoemaker SE, Zhou J, Zhong J, Wu Y, Bonder D, Hollenback S, Coppola G, Geschwind DH, Landreth GE, Snider WD.
Specific functions for ERK/MAPK signaling during PNS development.
Neuron. 2011 Jan 13;69(1):91-105. doi: 10.1016/j.neuron.2010.12.003.
Full-Text on PubMed
Cho Lab
PUBLICATION: 
Journal Article
Bao Y, Kim E, Bhosle S, Mehta H, Cho S.
A role for spleen monocytes in post-ischemic brain inflammation and injury.
J Neuroinflammation. 2010 Dec 15;7:92. doi: 10.1186/1742-2094-7-92.
Abstract on PubMed
GRANT: 
Federal
April 1, 2010 to March 31, 2015
Retinal Neural Processing During Retinal Degenerative Diseases
Funding Status: 
Completed Project
National Institutes of Health (NIH)
National Eye Institute (NEI)
Grant Number: 
R01EY020535
Investigators: 
Botir T. Sagdullaev, Ph.D.
Principal Investigator
Gibson Lab
PUBLICATION: 
Journal Article
Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA, Schon EA.
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria.
Am J Pathol. 2009 Nov;175(5):1810-6. doi: 10.2353/ajpath.2009.090219.
Full-Text on PubMed
PUBLICATION: 
Manuscript
Ivanova E, Pan ZH.
Evaluation of the adeno-associated virus mediated long-term expression of channelrhodopsin-2 in the mouse retina.
Molecular Vision. 2009 Aug 21; 15: 1680-1689
Full-Text on PubMed

Causes

Motor Recovery, Pain & Sensory Recovery, Stroke, Spinal Cord Injury, Cognitive Recovery, Neurodegenerative Diseases, Vision Recovery, Retinal Degenerative Diseases