Megan Bourassa, Ph.D.

Former Postdoctoral Fellow

Laboratory for Neural Redox Biology and Homeostatic Transcription

Burke Neurological Institute

Recent Publications

PUBLICATION:

Manuscript

Marietta Zille, Amit Kumar, Nandini Kundu, Megan W. Bourassa, Victor S. C. Wong, Dianna Willis, Saravanan S. Karuppagounder and Rajiv R. Ratan

Ferroptosis in neurons and cancer cells is similar but differentially regulated by histone deacetylase inhibitors

eNeuro. 2019 Feb 15;6(1). pii: ENEURO.0263-18.2019. doi: 10.1523/ENEURO.0263-18.2019. eCollection 2019 Jan-Feb.

Full-Text on Pubmed

Ratan Lab

PUBLICATION:

Journal Article

Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA, Kumar A, Perry S, Pinto JT, Darley-Usmar V, Sanchez S, Milne GL8, Pratico D, Holman TR, Carmichael ST, Coppola G, Colbourne F, Ratan RR.

N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with PGE2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice.

Ann Neurol. 2018 Dec;84(6):854-872. doi: 10.1002/ana.25356. Epub 2018 Nov 29.

Full-Text on Pubmed

Ratan Lab

PUBLICATION:

Journal Article

Gaisina IN, Lee SH, Kaidery NA, Ben Aissa M, Ahuja M, Smirnova NN, Wakade S, Gaisin A, Bourassa MW, Ratan RR, Nikulin SV, Poloznikov AA, Thomas B, Thatcher GRJ, Gazaryan IG.

Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors.

ACS Chem Neurosci. 2018 May 16;9(5):894-900. doi: 10.1021/acschemneuro.7b00435. Epub 2018 Jan 17.

Full-Text on Pubmed

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Ratan Lab

Causes

Motor Recovery, Pain & Sensory Recovery, Cognitive Recovery, Stroke, Spinal Cord Injury, Traumatic Brain Injury, Neurodegenerative Diseases

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Megan Bourassa, Ph.D.

Recent Publications

Connect

Associated

Causes