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Targeting oxidative distress to treat chemobrain: Go with the choroid plexus-cerebrospinal fluid flow
Publisher:Neuron. 2022 Oct 19;110(20):3219-3222. doi: 10.1016/j.neuron.2022.09.016.
Identifiers:PMID: 36265438 | DOI: 10.1016/j.neuron.2022.09.016
Chemobrain is a variable but debilitating consequence of lifesaving cancer treatments. In this issue of Neuron, Jang and colleagues provide a new conceptual framework based on choroid plexus-CSF antioxidant status that advances understanding of chemobrain's nervous system pathobiology and identifies novel therapeutic opportunities.