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Molecular Studies

Impact

RESEARCH PROJECT: 
In Progress

Mitochondrial dysfunction and oxidative stress are consistent features of multiple neurodegenerative diseases including Alzheimer’s disease (AD).

RESEARCH PROJECT: 
In Progress

Because strategies that promote acute neuroprotection have not successfully translated into clinical practice, studies to understand repair/recovery mechanisms that promote functional recovery have emerged.

RESEARCH PROJECT: 
In Progress

The recurring failure to translate neuroprotective strategies in animal models into clinical settings prompted us to reevaluate existing preclinical stroke models.

RESEARCH PROJECT: 
In Progress

Nucleic acid secondary structures, such as G-quadruplexes and i-motifs, are emerging as important regulators of gene expression in the nervous system.

RESEARCH PROJECT: 
In Progress

This project focuses onhow phenotypes of neurons generated in the adult subventricular zone (SVZ) are specified and how these neurons integrate into matureolfactory bulb circuits.

RESEARCH PROJECT: 
In Progress

Stroke-induced brain injury has been viewed mainly from a neurocentric perspective, with much attention given to the primary injury site and its penumbra.

GRANT: 
Federal
April 15, 2016 to March 31, 2021
Grant Number: 
P01AG014930
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Investigators: 
GRANT: 
Federal
April 1, 2016 to March 31, 2021
Grant Number: 
R01EY026576
National Institutes of Health (NIH)
National Eye Institute (NEI)
Investigators: 
Principal Investigator
GRANT: 
Non-Federal
December 15, 2015 to December 15, 2016
Sanofi iAward
Investigators: 
Principal Investigator
PUBLICATION: 
Journal Article
Kim E, Woo MS, Qin L, Ma T, Beltran CD, Bao Y, Bailey JA, Corbett D, Ratan RR, Lahiri DK, Cho S.
J Neurosci. 2015 Nov 11;35(45):15113-26. doi: 10.1523/JNEUROSCI.2890-15.2015.
Abstract on PubMed