Carmel Lab
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Jason B. Carmel, M.D., Ph.D.
Jason B. Carmel, M.D., Ph.D.
FACULTY - LAB DIRECTOR

Jason B. Carmel, M.D., Ph.D.

Director
Motor Recovery Laboratory, Burke-Blythedale Hemiplegia Center, Early Brain Injury Recovery Clinic
Burke Medical Research Institute
Assistant Professor of Neuroscience
Weill Cornell Medicine
Assistant Professor of Neuroscience in Pediatrics
Weill Cornell Medicine
Assistant Professor of Neurology
Weill Cornell Medicine
Attending Neurologist

Biography

I am a child neurologist and motor system neuroscientist interested in central nervous system injury and repair. During my postdoctoral fellowship in Jack Martin’s laboratory, I developed expertise in corticospinal injury and response to activity-based treatments. Using a combination of anatomy, physiology (brain mapping), and behavior, I have been able to identify the brain circuits that adapt to developmental brain injury.

My laboratory uses activity-based therapies, including brain stimulation and intensive behavioral training to promote recovery of function, both in rodents and humans. In a rodent hemiparesis model, we have demonstrated that stimulation of spared motor circuits causes them to sprout at their terminations in the spinal cord, form functional connections with spinal motor circuits, and restore motor skill.

My expertise in animal models of human disease and clinical neurology will allow me to translate the gains in understanding that we hope to achieve in the proposed studies into improved treatments for children with cerebral palsy. This is my goal as a physician-scientist: to direct a truly translational program in which we model activity-based repair strategies in young animals with early brain injury and then use those results to design better treatments for children at risk for cerebral palsy.

Board Certification     
American Board of Psychiatry and Neurology, Special Qualification in Child Neurology

Instructor                  
Department of Neurology, Columbia University, New York

Education

Degree: 
Resident, Neurology
Institution: 
Department of NeurologyColumbia University, New York
Degree: 
Intern, Pediatrics
Institution: 
Children’s Hospital of New YorkColumbia University, New York
Degree: 
Ph.D., Neuroscience
Institution: 
Laboratory of Wise Young and Ronald HartRutgers University, Piscataway, New Jersey
Degree: 
M.D.
Institution: 
Columbia University College of Physicians and Surgeons, New York
Degree: 
B.A.
Institution: 
Stanford University, Stanford, California

Recent Publications

PUBLICATION: 
Journal Article
Sindhurakar A, Mishra AM, Gupta D, Iaci JF, Parry TJ, Carmel JB.
Neurorehabil Neural Repair. 2017 Jan 1:1545968316688800. doi: 10.1177/1545968316688800. [Epub ahead of print]
Abstract on PubMed
PUBLICATION: 
Journal Article
Harel NY, Carmel JB.
Neural Plast. 2016;2016:7043767. Review.
Abstract on PubMed
PUBLICATION: 
Journal Article
Sindhurakar A, Butensky SD, Meyers E, Santos J, Bethea T, Khalili A, Sloan AP, Rennaker RL 3rd, Carmel JB.
Neurorehabil Neural Repair. 2017 Feb;31(2):122-132. doi: 10.1177/1545968316662528.
Abstract on PubMed