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Metabolism

Impact

RESEARCH PROJECT: 
Complete
Thiamine (vitamin B1) dependent processes are reduced in Alzheimer’s disease. Thiamine deficiency mimics many aspects of Alzheimer’s disease including the reduced glucose metabolism and exaggeration of the plaque and tangle pathology.
PRESENTATION: 
Poster Presentation
July 16, 2017 to July 20, 2017
Venue: 
Alzheimer's Association International Conference, London, England
PRESENTATION: 
Conference
July 16, 2017 to July 20, 2017
Venue: 
Alzheimer's Association International Conference, London, England
PUBLICATION: 
Journal Article
Chen H, Xu H, Potash S, Starkov A, Belousov VV, Bilan DS, Denton TT, Gibson GE.
J Neurosci Res. 2017 Jun 20. doi: 10.1002/jnr.24103. [Epub ahead of print]
Abstract on PubMed
PUBLICATION: 
Review
Gibson GE, Thakkar A.
Neurochem Int. 2017 Jun 13. pii: S0197-0186(17)30332-7. doi: 10.1016/j.neuint.2017.06.007. [Epub ahead of print]
Abstract on PubMed
PRESENTATION: 
Seminar
May 3, 2017
Venue: 
Montefiore Hudson Valley, Center of Excellence for Alzheimer’s Disease (CEAD), Bronx, NY
PUBLICATION: 
Journal Article
Gibson GE, Thakkar A.
Neurochem Res. 2017 Jun;42(6):1636-1648. doi: 10.1007/s11064-017-2182-3. Epub 2017 Feb 8.
Abstract on PubMed
PUBLICATION: 
Journal Article
Naseri NN, Bonica J, Xu H, Park LC, Arjomand J, Chen Z, Gibson GE.
PLoS One. 2016 Sep 9;11(9):e0160384. doi: 10.1371/journal.pone.0160384.
Full-Text on PubMed
PUBLICATION: 
Journal Article
Chen H, Denton TT, Xu H, Calingasan N, Beal MF, Gibson GE.
J Neurochem. 2016 Dec;139(5):823-838. doi: 10.1111/jnc.13836.
Abstract on PubMed
GRANT: 
Federal
April 15, 2016 to March 31, 2021
Funding Status: 
Active Project
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Grant Number: 
P01AG014930
Investigators: