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Drug Discovery

Impact

NEWS: 
Article

On March 2nd, a manuscript from the Burke Medical Research Institute describing a novel drug for improving outcomes following brain hemorrhage was published in Science’s sister journal, Science Translational Medicine.

BMRI Researchers Discover a Novel Drug to Prevent Brain Bleeding
PUBLICATION: 
Journal Article
Gibson GE, Hirsch JA, Fonzetti P, Jordan BD, Cirio RT, Elder J.
Ann N Y Acad Sci. 2016 Mar;1367(1):21-30. doi: 10.1111/nyas.13031. Epub 2016 Mar 11.
Abstract on PubMed
NEWS: 
In the Media
Media Outlet: 
Chemical & Engineering News
NEWS: 
In the Media
Media Outlet: 
ScienceDaily
PUBLICATION: 
Journal Article
Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR
Sci Transl Med. 2016 Mar 2;8(328):328ra29. doi: 10.1126/scitranslmed.aac6008.
Abstract on PubMed
GRANT: 
Non-Federal
October 1, 2015 to October 1, 2017
Adelson Medical Research Foundation
Investigators: 
Principal Investigator
CLINICAL TRIAL: 
In-Progress / Currently Recruiting Participants
November 10, 2014 to November 1, 2019
Cognitive Recovery, Neurodegenerative Diseases
GRANT: 
Federal
September 1, 2014 to May 31, 2019
Grant Number: 
R01AG043679
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Investigators: 
Principal Investigator
Principal Investigator
PUBLICATION: 
Journal Article
Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, Andersen JK, Ratan RR.
Antioxid Redox Signal. 2015 Jan 10;22(2):121-34. doi: 10.1089/ars.2013.5595.
Full-Text on PubMed
PUBLICATION: 
Journal Article
Haskew-Layton RE, Payappilly JB, Xu H, Bennett SA, Ratan RR.
J Neurochem. 2013 Feb;124(4):536-47. doi: 10.1111/jnc.12107.
Abstract on PubMed