Hill Lab

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Spinal Cord Injury Preclincal Studies

Hill laboratory focuses on spinal cord injury (SCI) repair and the development of therapeutic interventions to promote recovery of function. Studies range from examining the basic biology of axonal regeneration to testing small molecules and cellular transplants for their ability to promote axonal regeneration and functional recovery in rodent models of spinal cord injury. We are particularly interested in understanding the basic biology behind dystrophic axonal endings (retraction bulbs) that form when injured axons encounter the chronic lesion margin and developing strategies to promote the efficacy of cell transplants for spinal cord injury repair.

Understanding the basic biology behind dystrophic axonal ending formation.

Understanding the basic biology behind dystrophic axonal ending formation.

Enhancing the efficacy of cell transplants for SCI repair.

Enhancing the efficacy of cell transplants for SCI repair.

Featured Research Projects

RESEARCH PROJECT: 
In Progress

Testing therapeutic interventions in rodent models of SCIĀ for their ability to enhance axonal regeneration and behavioral recovery.

RESEARCH PROJECT: 
In Progress

Understanding the basic biology behind dystrophic axonal endingsĀ (retraction bulbs) that form when injured axons encounter the chronic lesion margin.

RESEARCH PROJECT: 
In Progress

Development of strategies to enhance the survival of transplanted cells, with a particular focus on Schwann cells (SCs) because of their potential for autologous use.

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Caitlin E. Hill, Ph.D.

Associated