The Fournier lab focuses on molecular mechanisms underlying nerve cell damage and repair following CNS injury. Neurons in the central nervous system undergo damage following acute injuries including spinal cord injury and in many neurodegenerative diseases including Multiple Sclerosis. Neurons fail to spontaneously regenerate following injury because of a non supportive environment at the lesion site and because of a failure to initiate intrinsic growth programs to drive regeneration. The Fournier lab focusses on understanding the molecular mechanisms underlying neuronal responses to injury to develop therapeutic strategies to promote neuroprotection and repair. The lab is currently focussing on targetting 14-3-3 adaptor proteins as a novel mechanism to promote axonal regeneration and on the role of miRNAs in neuronal damage in inflammatory conditions such as Multiple Sclerosis.