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Inflammation and Recovery after Intracerebral Hemorrhage

EVENT: 
Weekly Seminar
Who Should Attend: 
Researchers

Speakers

Guest Speaker
Lauren H. Sansing, MD, MS
Associate Professor
Department of Neurology, Human and Translational Immunology Program
Yale University School of Medicine

Dr. Sansing’s primary research focus has been on mechanisms of leukocyte recruitment and activation after ICH and the mechanisms of the resolution of inflammation and recovery. The desire to improve outcome after stroke incited this interest in inflammatory mechanisms of secondary brain injury. For the past seven years, her laboratory has investigated the role of innate immune responses after intracerebral hemorrhage in experimental murine in vivo and in vitro models, as well as ex vivo models using patient blood and surgical specimens. As a physician-scientist, her goal is to identify the pathological processes that lead to brain injury in our patients, as well as the processes that aid in recovery and repair. With this understanding, we can develop targeted therapeutics to minimize injury after stroke and maximize recovery.

Lauren H. Sansing, MD, MS Figure

Publications

Ridker PM, Revkin J, Amarenco P, Brunell R, Curto M, Civeira F, Flather M, Glynn RJ, Gregoire J, Jukema JW, Karpov Y, Kastelein JJP, Koenig W, Lorenzatti A, Manga P, Masiukiewicz U, Miller M, Mosterd A, Murin J, Nicolau JC, Nissen S, Ponikowski P, Santos RD, Schwartz PF, Soran H, White H, Wright RS, Vrablik M, Yunis C, Shear CL, Tardif JC; SPIRE Cardiovascular Outcome Investigators.
Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients.
N Engl J Med. 2017 Apr 20;376(16):1527-1539. doi: 10.1056/NEJMoa1701488. Epub 2017 Mar 17.
Paul M Ridker, M.D., Jean-Claude Tardif, M.D., Pierre Amarenco, M.D., William Duggan, Ph.D., Robert J. Glynn, Sc.D., J. Wouter Jukema, M.D., John J.P. Kastelein, M.D., Albert M. Kim, M.D., Ph.D., Wolfgang Koenig, M.D., Steven Nissen, M.D., James Revkin, M.D., Lynda M. Rose, M.S., Raul D. Santos, M.D., Ph.D., Pamela F. Schwartz, Ph.D., Charles L. Shear, Dr.P.H., and Carla Yunis, M.D., for the SPIRE Investigators.
Lipid-Reduction Variability and Antidrug-Antibody Formation with Bococizumab.
N Engl J Med 2017; 376:1517-1526; April 20, 2017
Søndergaard L, Kasner SE, Rhodes JF, Andersen G, Iversen HK, Nielsen-Kudsk JE, Settergren M, Sjöstrand C, Roine RO, Hildick-Smith D, Spence JD, Thomassen L; Gore REDUCE Clinical Study Investigators.
Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke.
N Engl J Med. 2017 Sep 14;377(11):1033-1042. doi: 10.1056/NEJMoa1707404.

When

Tuesday, November 28, 2017 - 12:30pm

Where

Burke Medical Research Institute
785 Mamaroneck Avenue
White Plains, NY 10605
United States
Conference Room: 
Billings Building – Rosedale

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