Non-invasive brain stimulation (tDCS or rTMS) is increasingly used in experimental clinical trials to augment behavioral therapy methods in restoration of function in survivors of neurological trauma and stroke. Post-stroke motor dysfunction has received much attention, given its importance in the residual disability of community dwelling patients, the high prevalence, and substantial economic impact. This lecture will present the rationale, methods, and results of two recent randomized, sham controlled, trials run through the Burke-Cornell Medical Research Institute. Here, chronic stroke patients with residual hemiparesis participated in a motor training regimen and had supplementary non-invasive stimulation. Results will be presented and future direction discussed.