Cortes Lab

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Human Spinal Cord Injury Repair Laboratory

Cortes Lab's research studies are oriented to understand and enhance the underlying mechanisms of motor dysfunction and enhance motor recovery after spinal cord injury in humans by using 3 approaches:

  1. The use of neurophysiology (transcranial magnetic stimulation, TMS), to investigate a) the functional integrity of the corticospinal system, as well as b) the specific pattern of reorganization in the primary motor cortex (TMS mapping) at chronic stages or during the rehabilitation process, and c) the spinal circuitry, by studying the H-reflex and its implication in motor recovery.
  2. The use of neuromodulatory interventions with the aim to strengthen the preserved corticospinal connections below the level of the injury targeting either the brain (using transcranial direct current stimulation, tDCS) or the spinal cord (using repetitive TMS combined with electrical stimulation, spinal associative stimulation, SAS).
  3. The use of repetitive behavioral interventions such as the use of upper-limb robotic devices, able to deliver precisely controlled high-dose therapy, as well as to objectively and reliably quantify motor dysfunction. 

Cortes Lab