Cave Lab
Research Projects

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Our laboratory studies mechanisms that regulate the proliferation and differentiation of adult neural stem cells, and the development of applications for this mechanistic knowledge to treat of neurological disease or injury. Much of our work is concentrated on molecular mechanisms that regulate gene expression.

Research Projects

RESEARCH PROJECT: 
In Progress

Nucleic acid secondary structures, such as G-quadruplexes and i-motifs, are emerging as important regulators of gene expression in the nervous system.

RESEARCH PROJECT: 
In Progress
This project explores transcription regulatory mechanisms that control cell adhesion gene expression.
RESEARCH PROJECT: 
In Progress

This project focuses onhow phenotypes of neurons generated in the adult subventricular zone (SVZ) are specified and how these neurons integrate into matureolfactory bulb circuits.

RESEARCH PROJECT: 
In Progress

Stem cells are an ideal source of neuronsto make cell replacement therapy a practical treatment strategy for Parkinson’s Disease.